Rutger W W Brouwer
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Explore the profile of Rutger W W Brouwer including associated specialties, affiliations and a list of published articles.
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53
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1494
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Recent Articles
1.
Seynhaeve A, Liu H, Priester M, Valentijn M, van Holten-Neelen C, Brouwer R, et al.
Cancer Res
. 2025 Feb;
PMID: 40009768
Tumor necrosis factor-alpha (TNFα) induces vascular permeability and plays an important role in inflammation. In addition, TNFα-induced vascular leakage is involved in the increased extravasation of nanoparticle-formulated chemotherapeutic drugs, improving...
2.
Byrou S, Brouwer R, Tomazou M, Tamana S, Kountouris P, Lederer C, et al.
Int J Mol Sci
. 2025 Jan;
26(2).
PMID: 39859286
Non-invasive prenatal testing (NIPT) has been widely adopted for the screening of chromosomal abnormalities; however, its adoption for monogenic disorders, such as β-thalassaemia, has proven challenging. Haemoglobinopathies are the most...
3.
Verploegh I, Conidi A, El Hassnaoui H, Verhoeven F, Korporaal A, Ntafoulis I, et al.
Int J Mol Sci
. 2024 Sep;
25(18).
PMID: 39337661
One of the main causes of poor prognoses in patient with glioblastoma (GBM) is drug resistance to current standard treatment, which includes chemoradiation and adjuvant temozolomide (TMZ). In addition, the...
4.
Hornung B, Azmani Z, den Dekker A, Oole E, Ozgur Z, Brouwer R, et al.
Genes (Basel)
. 2023 Dec;
14(12).
PMID: 38137048
Single cell RNAseq has been a big leap in many areas of biology. Rather than investigating gene expression on a whole organism level, this technology enables scientists to get a...
5.
van der List A, Litjens N, Brouwer R, Klepper M, den Dekker A, van IJcken W, et al.
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37833911
After kidney transplantation (KT), donor-specific hyporesponsiveness (DSH) of recipient T cells develops over time. Recently, apoptosis was identified as a possible underlying mechanism. In this study, both transcriptomic profiles and...
6.
Onrust-van Schoonhoven A, de Bruijn M, Stikker B, Brouwer R, Braunstahl G, van IJcken W, et al.
Sci Immunol
. 2023 Jul;
8(85):eadg3917.
PMID: 37418545
Memory T cells provide long-lasting defense responses through their ability to rapidly reactivate, but how they efficiently "recall" an inflammatory transcriptional program remains unclear. Here, we show that human CD4...
7.
Birkhoff J, Korporaal A, Brouwer R, Nowosad K, Milazzo C, Mouratidou L, et al.
Genes (Basel)
. 2023 Mar;
14(3).
PMID: 36980900
Functional perturbation and action mechanism studies have shown that the transcription factor Zeb2 controls cell fate decisions, differentiation, and/or maturation in multiple cell lineages in embryos and after birth. In...
8.
Isebia K, Mostert B, Belderbos B, Buck S, Helmijr J, Kraan J, et al.
Eur J Cancer
. 2022 Nov;
177:33-44.
PMID: 36323051
Background: Metastatic castration-resistant prostate cancer (mCRPC) patients with positive AR-V7 expression in their circulating tumour cells (CTCs) rarely derive benefit from abiraterone and enzalutamide. Design: We performed a prospective, multicenter,...
9.
Looijesteijn E, Brouwer R, Schoemaker R, Ulfman L, Ham S, Jeurink P, et al.
BMC Nutr
. 2022 Aug;
8(1):93.
PMID: 36038938
Background: Natural enrichment of sn-2 palmitate content of infant formulae by using bovine milk fat is known to reduce formation of faecal fatty acid soaps and to improve stool consistency,...
10.
Nowosad K, Brouwer R, Odrzywolski A, Korporaal A, Gielniewski B, Wojtas B, et al.
Sci Rep
. 2022 Jul;
12(1):12835.
PMID: 35896673
The formation of the synovial joint begins with the visible emergence of a stripe of densely packed mesenchymal cells located between distal ends of the developing skeletal anlagen called the...