Anders Wallqvist
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Explore the profile of Anders Wallqvist including associated specialties, affiliations and a list of published articles.
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168
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2091
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Recent Articles
11.
Goel H, Printz R, Shiota C, Estes S, Pannala V, AbdulHameed M, et al.
Int J Mol Sci
. 2023 Apr;
24(8).
PMID: 37108594
Acute kidney injury, which is associated with high levels of morbidity and mortality, affects a significant number of individuals, and can be triggered by multiple factors, such as medications, exposure...
12.
Tewari S, Elahi R, Kwan B, Rajaram K, Bhatnagar S, Reifman J, et al.
Malar J
. 2023 Feb;
22(1):56.
PMID: 36788578
Background: Spiroindolone and pyrazoleamide antimalarial compounds target Plasmodium falciparum P-type ATPase (PfATP4) and induce disruption of intracellular Na homeostasis. Recently, a PfATP4 mutation was discovered that confers resistance to a...
13.
Jin X, Laxminarayan S, Nagaraja S, Wallqvist A, Reifman J
Int J Numer Method Biomed Eng
. 2022 Nov;
39(1):e3662.
PMID: 36385572
Mathematical models of human cardiovascular and respiratory systems provide a viable alternative to generate synthetic data to train artificial intelligence (AI) clinical decision-support systems and assess closed-loop control technologies, for...
14.
Andagalu B, Lu P, Onyango I, Bergmann-Leitner E, Wasuna R, Odhiambo G, et al.
Front Med (Lausanne)
. 2022 Oct;
9:991807.
PMID: 36314027
The impact of pre-existing immunity on the efficacy of artemisinin combination therapy is largely unknown. We performed in-depth profiling of serological responses in a therapeutic efficacy study [comparing artesunate-mefloquine (ASMQ)...
15.
Enabling data-limited chemical bioactivity predictions through deep neural network transfer learning
Liu R, Laxminarayan S, Reifman J, Wallqvist A
J Comput Aided Mol Des
. 2022 Oct;
36(12):867-878.
PMID: 36272041
The main limitation in developing deep neural network (DNN) models to predict bioactivity properties of chemicals is the lack of sufficient assay data to train the network's classification layers. Focusing...
16.
Rajaram K, Tewari S, Wallqvist A, Prigge S
J Biol Chem
. 2022 Apr;
298(5):101897.
PMID: 35398098
In the glucose-rich milieu of red blood cells, asexually replicating malarial parasites mainly rely on glycolysis for ATP production, with limited carbon flux through the mitochondrial tricarboxylic acid (TCA) cycle....
17.
Stewart P, Williamson K, Boegli L, Hamerly T, White B, Scott L, et al.
Antimicrob Agents Chemother
. 2022 Mar;
66(4):e0002122.
PMID: 35266829
Is there a universal genetically programmed defense providing tolerance to antibiotics when bacteria grow as biofilms? A comparison between biofilms of three different bacterial species by transcriptomic and metabolomic approaches...
18.
Tewari S, Kwan B, Elahi R, Rajaram K, Reifman J, Prigge S, et al.
Sci Rep
. 2022 Jan;
12(1):1167.
PMID: 35064153
Due to the recurring loss of antimalarial drugs to resistance, there is a need for novel targets, drugs, and combination therapies to ensure the availability of current and future countermeasures....
19.
Schyman P, Printz R, Pannala V, AbdulHameed M, Estes S, Shiota C, et al.
Toxicol Appl Pharmacol
. 2021 Sep;
430:115713.
PMID: 34492290
To study the complex processes involved in liver injuries, researchers rely on animal investigations, using chemically or surgically induced liver injuries, to extrapolate findings and infer human health risks. However,...
20.
Nguyen H, Chaudhury S, Waickman A, Friberg H, Currier J, Wallqvist A
Front Immunol
. 2021 Sep;
12:696755.
PMID: 34484195
The dengue virus circulates as four distinct serotypes, where a single serotype infection is typically asymptomatic and leads to acquired immunity against that serotype. However, the developed immunity to one...