Anders Hojgaard Hansen
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Explore the profile of Anders Hojgaard Hansen including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
161
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Recent Articles
11.
Domljanovic I, Hansen A, Hansen L, Klitgaard J, Taskova M, Astakhova K
Nucleic Acid Ther
. 2018 Aug;
28(6):348-356.
PMID: 30106665
Synthetic oligonucleotides, their complexes and conjugates with other biomolecules represent valuable research tools and therapeutic agents. In spite of growing applications in basic research and clinical science, only few studies...
12.
Sergeev E, Hansen A, Bolognini D, Kawakami K, Kishi T, Aoki J, et al.
Sci Rep
. 2017 Oct;
7(1):13741.
PMID: 29061999
Free Fatty Acid Receptor 2 is a GPCR activated by short chain fatty acids produced in high levels in the lower gut by microbial fermentation of non-digestible carbohydrates. A major...
13.
Hansen A, Sergeev E, Pandey S, Hudson B, Christiansen E, Milligan G, et al.
J Med Chem
. 2017 Jun;
60(13):5638-5645.
PMID: 28570808
The free fatty acid receptor 2 (FFA2/GPR43) is considered a potential target for treatment of metabolic and inflammatory diseases. Here we describe the development of the first fluorescent tracer for...
14.
Bjorkman L, Martensson J, Winther M, Gabl M, Holdfeldt A, Uhrbom M, et al.
Mol Cell Biol
. 2016 Aug;
36(20):2583-95.
PMID: 27503855
Ligands with improved potency and selectivity for free fatty acid receptor 2 (FFA2R) have become available, and we here characterize the neutrophil responses induced by one such agonist (Cmp1) and...
15.
Hansen A, Lomholt M, Hansen P, Mouritsen O, Arouri A
Int J Pharm
. 2016 May;
508(1-2):128-34.
PMID: 27163524
We carried out a mechanistic study to characterize and optimize the remote loading of luciferin into preformed liposomes of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine/1,2-dipalmitoyl-sn-glycero-3-phosphoglycerol (DPPC/DPPG) 7:3 mixtures. The influence of the loading agent (acetate,...
16.
Christiansen E, Hudson B, Hansen A, Milligan G, Ulven T
J Med Chem
. 2016 Apr;
59(10):4849-58.
PMID: 27074625
The free fatty acid receptor 1 (FFA1/GPR40) is a potential target for treatment of type 2 diabetes. Although several potent agonists have been described, there remains a strong need for...
17.
Sergeev E, Hansen A, Pandey S, MacKenzie A, Hudson B, Ulven T, et al.
J Biol Chem
. 2015 Nov;
291(1):303-17.
PMID: 26518871
Short chain fatty acids (SCFAs) are produced in the gut by bacterial fermentation of poorly digested carbohydrates. A key mediator of their actions is the G protein-coupled free fatty acid...
18.
Hudson B, Christiansen E, Murdoch H, Jenkins L, Hansen A, Madsen O, et al.
Mol Pharmacol
. 2014 May;
86(2):200-10.
PMID: 24870406
Analysis of the roles of the short chain fatty acid receptor, free fatty acid 3 receptor (FFA3), has been severely limited by the low potency of its endogenous ligands, the...
19.
Hansen A, Sorensen K, Mathieu R, Serer A, Duelund L, Khandelia H, et al.
Chem Phys Lipids
. 2013 Sep;
175-176:84-91.
PMID: 23994552
The compound 2,6-diisopropylphenol (Propofol, PRF) is widely used for inducing general anesthesia, but the mechanism of PRF action remains relatively poorly understood at the molecular level. This work examines the...