Anastasia Sacharidou
Overview
Explore the profile of Anastasia Sacharidou including associated specialties, affiliations and a list of published articles.
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31
Citations
1208
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Recent Articles
1.
Papaetis G, Sacharidou A, Michaelides I, Mikellidis K, Karvounaris S
Curr Cardiol Rev
. 2024 Oct;
PMID: 39415589
Insulin resistance describes the lack of activity of a known quantity of insulin (exogenous or endogenous) to promote the uptake of glucose and its utilization in an individual, as much...
2.
Sacharidou A, Chambliss K, Peng J, Barrera J, Tanigaki K, Luby-Phelps K, et al.
Nat Commun
. 2023 Aug;
14(1):4989.
PMID: 37591837
The estrogen receptor (ER) designated ERα has actions in many cell and tissue types that impact glucose homeostasis. It is unknown if these include mechanisms in endothelial cells, which have...
3.
Yu L, Xu L, Chu H, Peng J, Sacharidou A, Hsieh H, et al.
Nat Commun
. 2023 Jul;
14(1):4101.
PMID: 37491347
Hypercholesterolemia and vascular inflammation are key interconnected contributors to the pathogenesis of atherosclerosis. How hypercholesterolemia initiates vascular inflammation is poorly understood. Here we show in male mice that hypercholesterolemia-driven endothelial...
4.
Calvier L, Manouchehri N, Sacharidou A, Mineo C, Shaul P, Hui D, et al.
Sci Immunol
. 2021 Aug;
6(62).
PMID: 34452924
Under normal conditions, the blood-brain barrier effectively regulates the passage of immune cells into the central nervous system (CNS). However, under pathological conditions such as multiple sclerosis (MS), leukocytes, especially...
5.
Chu H, Sacharidou A, Nguyen A, Li C, Chambliss K, Salmon J, et al.
Circ Res
. 2021 Aug;
129(7):735-750.
PMID: 34404233
[Figure: see text].
6.
Calvier L, Xian X, Lee R, Sacharidou A, Mineo C, Shaul P, et al.
Arterioscler Thromb Vasc Biol
. 2021 Feb;
41(4):1309-1318.
PMID: 33626909
[Figure: see text].
7.
Calvier L, Demuth G, Manouchehri N, Wong C, Sacharidou A, Mineo C, et al.
Sci Transl Med
. 2020 Aug;
12(556).
PMID: 32801146
Neuroinflammation as a result of immune cell recruitment into the central nervous system (CNS) is a key pathogenic mechanism of multiple sclerosis (MS). However, current anti-inflammatory interventions depleting immune cells...
8.
Peng J, Vongpatanasin W, Sacharidou A, Kifer D, Yuhanna I, Banerjee S, et al.
Circulation
. 2019 Oct;
140(24):2005-2018.
PMID: 31597453
Background: Obesity-related hypertension is a common disorder, and attempts to combat the underlying obesity are often unsuccessful. We previously revealed that mice globally deficient in the inhibitory immunoglobulin G (IgG)...
9.
Sacharidou A, Chambliss K, Ulrich V, Salmon J, Shen Y, Herz J, et al.
Blood
. 2018 Mar;
131(19):2097-2110.
PMID: 29500169
In the antiphospholipid syndrome (APS), antiphospholipid antibody (aPL) recognition of β2 glycoprotein I promotes thrombosis, and preclinical studies indicate that this is due to endothelial nitric oxide synthase (eNOS) antagonism...
10.
Tanigaki K, Sacharidou A, Peng J, Chambliss K, Yuhanna I, Ghosh D, et al.
J Clin Invest
. 2017 Dec;
128(1):309-322.
PMID: 29202472
Type 2 diabetes mellitus (T2DM) is a common complication of obesity. Here, we have shown that activation of the IgG receptor FcγRIIB in endothelium by hyposialylated IgG plays an important...