George E Davis
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Explore the profile of George E Davis including associated specialties, affiliations and a list of published articles.
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102
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5539
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Recent Articles
1.
Yrigoin K, Bernard K, Castano M, Cleaver O, Sumanas S, Davis G
Front Cell Dev Biol
. 2024 Nov;
12:1465806.
PMID: 39544367
In this study, we identify and characterize new molecular determinants that optimize human capillary tube network assembly. Our lab has previously reported a novel, serum free-defined 3D co-culture model using...
2.
Selective mural cell recruitment of pericytes to networks of assembling endothelial cell-lined tubes
Yrigoin K, Davis G
Front Cell Dev Biol
. 2024 Jul;
12:1389607.
PMID: 38961866
Mural cells are critically important for the development, maturation, and maintenance of the blood vasculature. Pericytes are predominantly observed in capillaries and venules, while vascular smooth muscle cells (VSMCs) are...
3.
Schumacher J, Wright Z, Rufin Florat D, Anand S, Dasyani M, Batta S, et al.
PLoS Genet
. 2024 Jan;
20(1):e1010851.
PMID: 38190417
Blood vessels in different vascular beds vary in size, which is essential for their function and fluid flow along the vascular network. Molecular mechanisms involved in the formation of a...
4.
Lin P, Sun Z, Davis G
Am J Pathol
. 2023 Oct;
194(4):574-598.
PMID: 37838010
This study sought to define key molecules and signals controlling major steps in vascular morphogenesis, and how these signals regulate pericyte recruitment and pericyte-induced basement membrane deposition. The morphogenic impact...
5.
Lin P, Koller G, Davis G
Am J Pathol
. 2023 Sep;
193(12):2203-2217.
PMID: 37689384
Five growth factors [ie, insulin, fibroblast growth factor-2 (FGF-2), stem cell factor, IL-3, and stromal-derived factor 1α] in combination are necessary for human endothelial cells (ECs) to undergo tube morphogenesis,...
6.
Schumacher J, Wright Z, Rufin Florat D, Anand S, Dasyani M, Klimkaite L, et al.
bioRxiv
. 2023 Jul;
PMID: 37461480
Blood vessels in different vascular beds vary in lumen diameter, which is essential for their function and fluid flow along the vascular network. Molecular mechanisms involved in the formation of...
7.
Lin P, Davis G
Arterioscler Thromb Vasc Biol
. 2023 Jul;
43(9):1599-1616.
PMID: 37409533
Because of structural and cellular differences (ie, degrees of matrix abundance and cross-linking, mural cell density, and adventitia), large and medium-sized vessels, in comparison to capillaries, react in a unique...
8.
Davis G, Davis M, Lowell W
Heliyon
. 2023 Jun;
9(6):e16954.
PMID: 37346332
Background And Objectives: Medical science needs to further elucidate the role of ultraviolet radiation (UVR), geographic latitude, and the role of vitamin D in the autoimmune disease multiple sclerosis (MS)....
9.
Sun Z, Lin P, Yrigoin K, Kemp S, Davis G
Am J Pathol
. 2023 Jun;
193(9):1319-1334.
PMID: 37328101
This study sought to identify potential mechanisms by which k-RasV12-expressing endothelial cell (EC) tubes demonstrate an increased propensity to regress compared with controls. Activated k-Ras mutations play a role in...
10.
Kemp S, Lin P, Sun Z, Castano M, Yrigoin K, Penn M, et al.
Front Cell Dev Biol
. 2022 Sep;
10:943533.
PMID: 36072343
Here we address the functional importance and role of pericytes in capillary tube network assembly, an essential process that is required for vascularized tissue development, maintenance, and health. Healthy capillaries...