Anand Selvaraj
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Explore the profile of Anand Selvaraj including associated specialties, affiliations and a list of published articles.
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1836
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Recent Articles
1.
Selvamani N, Shanmugasundaram R, Selvaraj A, Ranganathan G, Abraham S, Kirubakaran A
J Contemp Dent Pract
. 2023 Jun;
23(8):801-806.
PMID: 37283014
Aim: To find and compare the amount of screw loosening in gold and titanium alloy abutment screws without any cyclic load, this study was performed. Materials And Methods: A total...
2.
Zhao X, Joshi J, Aird D, Karr C, Yu K, Huang C, et al.
Am J Cancer Res
. 2022 Jul;
12(6):2733-2743.
PMID: 35812049
Hepatocellular carcinoma (HCC) is an aggressive liver malignancy that is difficult to treat with no approved biomarker based targeted therapies. FGF19-FGFR4 signaling blockade has been recently identified as a promising...
3.
Liao Y, Chan Y, Molakaseema V, Selvaraj A, Chen H, Wang Y, et al.
ACS Omega
. 2022 Jul;
7(26):22896-22905.
PMID: 35811872
An efficient solid-phase method has been reported to prepare well-defined lysine defect dendrimers. Using orthogonally protected lysine residues, pure G2 to G4 lysine defect dendrimers were prepared with 48-95% yields...
4.
Molakaseema V, Selvaraj A, Chen H, Chen Y, Liu Y, Kao C
J Org Chem
. 2021 Oct;
87(1):1-9.
PMID: 34677067
A rapid on-bead convergent method for preparing branched peptides was reported. Linear peptides were prepared on Dbz resin and ligated various branched cores, including lysine dendrons and other dendritic compounds....
5.
Brawn R, Cook A, Omoto K, Ke J, Karr C, Colombo F, et al.
ACS Med Chem Lett
. 2021 Jan;
12(1):93-98.
PMID: 33488969
Fibroblast growth factor receptors (FGFR) 2 and 3 have been established as drivers of numerous types of cancer with multiple drugs approved or entering late stage clinical trials. A limitation...
6.
Yao S, Nguyen T, Rolfe A, Agrawal A, Ke J, Peng S, et al.
Cell Chem Biol
. 2020 Feb;
27(3):259-268.e5.
PMID: 32017919
Carbamoyl phosphate synthetase 1 (CPS1) catalyzes the first step in the ammonia-detoxifying urea cycle, converting ammonia to carbamoyl phosphate under physiologic conditions. In cancer, CPS1 overexpression supports pyrimidine synthesis to...
7.
Nguyen T, Yao S, Wang Y, Rolfe A, Selvaraj A, Darman R, et al.
J Biol Chem
. 2019 Oct;
294(45):16966-16977.
PMID: 31582562
DNMT3A (DNA methyltransferase 3A) is a DNA methyltransferase responsible for establishing CpG methylation patterns within the genome. DNMT3A activity is essential for normal development, and its dysfunction has been linked...
8.
Korpal M, Puyang X, Wu Z, Seiler R, Furman C, Oo H, et al.
Nat Commun
. 2019 Jun;
10(1):2527.
PMID: 31164653
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
9.
Selvaraj A, Chen H, Huang A, Kao C
Chem Sci
. 2018 Apr;
9(2):345-349.
PMID: 29629103
A convenient and efficient chemical toolbox was developed for the on-resin C-terminal functionalization of various peptides. By transforming resin-bound 3,4-diaminobenzoic acid species with isoamyl nitrite, the resulting resin-bound benzotriazole entity...
10.
Joshi J, Coffey H, Corcoran E, Tsai J, Huang C, Ichikawa K, et al.
Cancer Res
. 2017 Dec;
77(24):6999-7013.
PMID: 29247039
Activation of the fibroblast growth factor receptor FGFR4 by FGF19 drives hepatocellular carcinoma (HCC), a disease with few, if any, effective treatment options. While a number of pan-FGFR inhibitors are...