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Anand Selvaraj

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Articles 25
Citations 1836
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Recent Articles
11.
Korpal M, Puyang X, Wu Z, Seiler R, Furman C, Oo H, et al.
Nat Commun . 2017 Jul; 8(1):103. PMID: 28740126
Muscle-invasive bladder cancer (MIBC) is an aggressive disease with limited therapeutic options. Although immunotherapies are approved for MIBC, the majority of patients fail to respond, suggesting existence of complementary immune...
12.
Darman R, Seiler M, Agrawal A, Lim K, Peng S, Aird D, et al.
Cell Rep . 2015 Nov; 13(5):1033-45. PMID: 26565915
Recurrent mutations in the spliceosome are observed in several human cancers, but their functional and therapeutic significance remains elusive. SF3B1, the most frequently mutated component of the spliceosome in cancer,...
13.
Ganapathy D, Joseph S, Ariga P, Selvaraj A
Dent Res J (Isfahan) . 2013 Jul; 10(1):87-92. PMID: 23878569
Background: Candidal colonization in complete denture wearers is a commonly encountered condition that worsens in the presence of untreated Diabetes Mellitus. The aim of this study was to evaluate the...
14.
Ganapthy D, Ariga P, Selvaraj A
Indian J Dent Res . 2012 Oct; 23(3):434. PMID: 23059595
Sublingual mode of drug administration is one of the fastest and predictable methods of drug delivery to the patient. Some patients, due to the pathological or psychological reasons, experience considerable...
15.
Kalender A, Selvaraj A, Thomas G
Cell Res . 2011 Apr; 21(6):859-61. PMID: 21483449
No abstract available.
16.
Dowling R, Topisirovic I, Alain T, Bidinosti M, Fonseca B, Petroulakis E, et al.
Science . 2010 May; 328(5982):1172-6. PMID: 20508131
The mammalian target of rapamycin complex 1 (mTORC1) integrates mitogen and nutrient signals to control cell proliferation and cell size. Hence, mTORC1 is implicated in a large number of human...
17.
Kalender A, Selvaraj A, Kim S, Gulati P, Brule S, Viollet B, et al.
Cell Metab . 2010 May; 11(5):390-401. PMID: 20444419
Dysfunctional mTORC1 signaling is associated with a number of human pathologies owing to its central role in controlling cell growth, proliferation, and metabolism. Regulation of mTORC1 is achieved by the...
18.
Selvaraj A, Thomas G
Cell Metab . 2010 Apr; 11(4):245-7. PMID: 20374954
Nutrients such as amino acids (aa) and glucose mediate mammalian target of rapamycin complex 1 (mTORC1) signaling to control cell growth and metabolism. Recent studies (Yan et al., 2010) identify...
19.
Dann S, Selvaraj A, Thomas G
Trends Mol Med . 2007 Apr; 13(6):252-9. PMID: 17452018
Recent studies demonstrate that the mammalian target of rapamycin (mTOR) and its effector, S6 kinase 1 (S6K1), lie at the crossroads of a nutrient-hormonal signaling network that is involved in...
20.
Yepiskoposyan H, Egli D, Fergestad T, Selvaraj A, Treiber C, Multhaup G, et al.
Nucleic Acids Res . 2006 Sep; 34(17):4866-77. PMID: 16973896
All organisms are confronted with external variations in trace element abundance. To elucidate the mechanisms that maintain metal homeostasis and protect against heavy metal stress, we have determined the transcriptome...