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Ana Vasileva

Explore the profile of Ana Vasileva including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 432
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Recent Articles
1.
Rohn T, Radin D, Brandmeyer T, Linder B, Andriambeloson E, Wagner S, et al.
PNAS Nexus . 2023 Jun; 2(6):pgad170. PMID: 37346271
The expanding field of precision gene editing using CRISPR/Cas9 has demonstrated its potential as a transformative technology in the treatment of various diseases. However, whether this genome-editing tool could be...
2.
Mazloom A, Xu H, Reig-Palou J, Vasileva A, Roman A, Mulero-Navarro S, et al.
Front Cell Dev Biol . 2022 Jun; 10:820255. PMID: 35652095
Characterization of pluripotent states, in which cells can both self-renew or differentiate, with the irreversible loss of pluripotency, are important research areas in developmental biology. Although microRNAs (miRNAs) have been...
3.
Mendoza R, Bi C, Cheng H, Gabutan E, Pagaspas G, Khan N, et al.
EClinicalMedicine . 2021 Jul; 38:101028. PMID: 34308321
Background: The negative impact of continued school closures during the height of the COVID-19 pandemic warrants the establishment of cost-effective strategies for surveillance and screening to safely reopen and monitor...
4.
Sevilla A, Papatsenko D, Mazloom A, Xu H, Vasileva A, Unwin R, et al.
Front Cell Dev Biol . 2021 Apr; 9:630067. PMID: 33816475
Cell fate decisions during development are governed by multi-factorial regulatory mechanisms including chromatin remodeling, DNA methylation, binding of transcription factors to specific loci, RNA transcription and protein synthesis. However, the...
5.
Mendoza R, Fyke W, Daniel D, Gabutan E, Das B, Bajaj H, et al.
Hum Immunol . 2021 Feb; 82(4):255-263. PMID: 33640208
Early in the SARS-CoV-2 pandemic, convalescent plasma (CP) therapy was proposed as a treatment for severely ill patients. We conducted a CP treatment protocol under the Mayo Clinic Extended Access...
6.
Castel S, Cervera A, Mohammadi P, Aguet F, Reverter F, Wolman A, et al.
Nat Genet . 2018 Aug; 50(9):1327-1334. PMID: 30127527
Coding variants represent many of the strongest associations between genotype and phenotype; however, they exhibit inter-individual differences in effect, termed 'variable penetrance'. Here, we study how cis-regulatory variation modifies the...
7.
Martinerie L, Manterola M, Chung S, Panigrahi S, Weisbach M, Vasileva A, et al.
PLoS Genet . 2014 Mar; 10(2):e1004165. PMID: 24586195
Loss of function of cyclin E1 or E2, important regulators of the mitotic cell cycle, yields viable mice, but E2-deficient males display reduced fertility. To elucidate the role of E-type...
8.
Lyndaker A, Vasileva A, Wolgemuth D, Weiss R, Lieberman H
Cell Cycle . 2013 Sep; 12(19):3135-45. PMID: 24013428
The RAD9A-RAD1-HUS1 (9-1-1) complex is a PCNA-like heterotrimeric clamp that binds damaged DNA to promote cell cycle checkpoint signaling and DNA repair. While various 9-1-1 functions in mammalian somatic cells...
9.
Vasileva A, Hopkins K, Wang X, Weisbach M, Friedman R, Wolgemuth D, et al.
J Cell Sci . 2013 Jun; 126(Pt 17):3927-38. PMID: 23788429
In mitotic cells, RAD9A functions in repairing DNA double-strand breaks (DSBs) by homologous recombination and facilitates the process by cell cycle checkpoint control in response to DNA damage. DSBs occur...
10.
Wolgemuth D, Manterola M, Vasileva A
Int J Dev Biol . 2013 Jun; 57(2-4):159-68. PMID: 23784826
Cyclins are key regulators of the mammalian cell cycle, functioning primarily in concert with their catalytic partners, the cyclin-dependent kinases (Cdks). While their function during mitosis in somatic cells has...