Ana Cristina Lima Leite
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Explore the profile of Ana Cristina Lima Leite including associated specialties, affiliations and a list of published articles.
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74
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Recent Articles
1.
Moura Y, Marques da Silva M, Cadete da Silva S, Nascimento T, Lima Leite A, Torres do Couto M, et al.
Biochimie
. 2025 Jan;
231:137-145.
PMID: 39746439
Fibrinolytic enzymes are promising in treating cardiovascular diseases due to their capacity to dissolve blood clots. The fibrinolytic enzyme from Arthrospira platensis (FEAP) was purified by ion exchange chromatography to...
2.
Gouveia de Melo Silva V, Manoel da Silva Sousa L, Fernandes Junior E, Brondani G, Maria de Albuquerque Oliveira I, Bedor D, et al.
Eur J Med Chem
. 2025 Jan;
284():117191.
PMID: 39742698
Trypanosomatidae diseases, such as Chagas disease and leishmaniasis, are caused by protozoan parasites of the Trypanosomatidae family, namely Trypanosoma cruzi and Leishmania species, respectively. There is an urgent need for...
3.
Lima Leite A, Nascimento T, da Cunha M, Mehari Y, Berger E, Scheich D, et al.
Int J Biol Macromol
. 2024 Jul;
275(Pt 2):133581.
PMID: 38960262
Secretory immunoglobulin A [sIgA] is a promising candidate for enteric therapeutics applications, and several sIgA-based constructs are currently being developed by groups utilizing clarified Chinese hamster ovary [CHO] cell culture...
4.
Cristovao-Silva A, Accioly Brelaz-de-Castro M, da Silva E, Lima Leite A, Santiago L, Conceicao J, et al.
Exp Parasitol
. 2024 Apr;
261:108749.
PMID: 38593864
Trypanosoma cruzi (T. cruzi) causes Chagas, which is a neglected tropical disease (NTD). WHO estimates that 6 to 7 million people are infected worldwide. Current treatment is done with benznidazole...
5.
Freitas L, Sousa C, Silva Lima B, Duarte D, de Moraes Gomes P, Ramos C, et al.
Chem Biol Interact
. 2024 Mar;
394:110954.
PMID: 38518852
The literature reports that thiazole and isatin nuclei present a range of biological activities, with an emphasis on anticancer activity. Therefore, our proposal was to make a series of compounds...
6.
Cox Holanda de Barros Dias M, Souza Barbalho M, Bezerra de Oliveira Filho G, de Oliveira Cardoso M, Lima Leite A, da Silva Santos A, et al.
Eur J Med Chem
. 2023 Jun;
257:115508.
PMID: 37267753
Chagas disease is a deadly and centenary neglected disease that is recently surging as a potential global threat. Approximately 30% of infected individuals develop chronic Chagas cardiomyopathy and current treatment...
7.
Pinto A, Nunes J, Severino Martins J, Leal A, Silva C, da Silva A, et al.
Curr Med Chem
. 2023 May;
31(20):2991-3032.
PMID: 37170994
Background: Cancer is a disease characterized by the abnormal multiplication of cells and is the second leading cause of death in the world. The search for new effective and safe...
8.
Conceicao J, da Silva Santos A, Brayner F, Alves L, Pinto A, Brondani G, et al.
Eur J Med Chem
. 2023 Apr;
254:115310.
PMID: 37062170
The present work reports the synthesis of a novel series of pyridine-thiazolidinones with anti-Trypanosoma cruzi and leishmanicidal activities (compounds 10-27), derived from 2 or 4-pyridine thiosemicarbazones (1-9). The in vitro...
9.
de Siqueira L, de Lima Ferreira L, Bezerra de Oliveira Filho G, de Oliveira M, Pinto A, Gouveia de Melo Silva V, et al.
Curr Top Med Chem
. 2022 Dec;
23(4):265-282.
PMID: 36573055
Background: Cancer is one of the most important barriers to increasing life expectancy in all countries in the 21st century. Investigations of new anti-cancer drugs with low side effects are...
10.
de Moraes Gomes P, Freitas L, Pessoa Siqueira L, Conceicao J, Dos Santos I, Pinto A, et al.
Curr Top Med Chem
. 2022 Dec;
23(6):426-439.
PMID: 36567284
Background: Zika virus (ZIKV) remains an important cause of congenital infection, fetal microcephaly, and Guillain-Barré syndrome in the population. In 2016, WHO declared a cluster of microcephaly cases and other...