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Fabio Andre Brayner

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Articles 64
Citations 499
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Recent Articles
1.
Gouveia de Melo Silva V, Manoel da Silva Sousa L, Fernandes Junior E, Brondani G, Maria de Albuquerque Oliveira I, Bedor D, et al.
Eur J Med Chem . 2025 Jan; 284():117191. PMID: 39742698
Trypanosomatidae diseases, such as Chagas disease and leishmaniasis, are caused by protozoan parasites of the Trypanosomatidae family, namely Trypanosoma cruzi and Leishmania species, respectively. There is an urgent need for...
2.
Ramos R, Reis E, Bezerra L, Lima M, Feitosa A, Alves L, et al.
Rev Soc Bras Med Trop . 2024 Nov; 57. PMID: 39536215
Background: Malaria is an acute febrile parasitic disease that significantly impacts global public health. In Brazil, the most studied endemic area for the disease is the Amazon region. This study...
3.
da Silva Alves A, de Sousa B, da Silva J, Veras D, Brayner F, Alves L, et al.
Braz J Microbiol . 2024 Aug; 55(4):3667-3677. PMID: 39110398
Candida species resistant to fluconazole have raised concern in the scientific medical community due to high mortality in patients with invasive disease. In developing countries, such as Brazil, fluconazole is...
4.
da Cruz Filho I, Duarte D, Marques D, da Rocha J, Diniz E, Brayner F, et al.
3 Biotech . 2023 Nov; 13(12):391. PMID: 37953832
Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-023-03799-2.
5.
de Lima F, de Araujo A, do Nascimento A, Bezerra Cavalcanti C, Oliveira Junior J, Sandes J, et al.
Braz J Microbiol . 2023 Oct; 54(4):2845-2856. PMID: 37904004
The high incidence of multidrug-resistant (MDR) Acinetobacter baumannii has been a challenge for health worldwide, due to the reduction of therapeutic options, making the use of antimicrobial combinations necessary for...
6.
Ferreira G, da Silva P, Lopes W, Feitosa A, Coelho L, Brayner F, et al.
J Appl Microbiol . 2023 Jul; 134(7). PMID: 37437916
Aims: We investigated the putative fungistatic and fungicidal activities of pomegranate sarcotesta lectin (PgTeL) against Cryptococcus neoformans B3501 (serotype D), specifically the ability of PgTeL to inhibit yeast capsule and...
7.
Oliveira Junior J, Rocha da Mota D, de Lima F, Higino T, Gutierrez S, Camara C, et al.
Microb Pathog . 2023 Jul; 182:106233. PMID: 37422173
Acinetobacter baumannii, a prominent emerging pathogen, is responsible for persistent and recurrent healthcare-associated infections (HAIs). Its bacterial resistance and virulence factors, such as biofilm formation, contribute to its survival in...
8.
Fagundes Silva H, de Araujo H, de Azevedo Albuquerque M, de Vasconcelos Lima M, Barroso Martins M, Alves L, et al.
Chem Biodivers . 2023 Jul; 20(8):e202300154. PMID: 37414744
Schistosomiasis affects about 260 million people worldwide and the search for new schistosomicidal compounds is urgent. In this study we evaluated the in vitro effect of barbatic acid against schistosomulae...
9.
Silva D, Nascimento P, da Rocha J, Marques D, Brayner F, Alves L, et al.
Acta Trop . 2023 Jun; 245:106965. PMID: 37295486
The present work aimed to carry out in vitro biological assays of thiazole compounds against adult worms of Schistosoma mansoni, as well as the in silico determination of pharmacokinetic parameters...
10.
Conceicao J, da Silva Santos A, Brayner F, Alves L, Pinto A, Brondani G, et al.
Eur J Med Chem . 2023 Apr; 254:115310. PMID: 37062170
The present work reports the synthesis of a novel series of pyridine-thiazolidinones with anti-Trypanosoma cruzi and leishmanicidal activities (compounds 10-27), derived from 2 or 4-pyridine thiosemicarbazones (1-9). The in vitro...