An Ning Cheng
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Explore the profile of An Ning Cheng including associated specialties, affiliations and a list of published articles.
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11
Citations
340
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Recent Articles
1.
Ko H, Peng H, Cheng A, Elizabeth Chou H, Hou H, Kuo W, et al.
Cancer Sci
. 2023 Aug;
114(10):3857-3872.
PMID: 37525561
The suppressive regulatory T cells (Treg) are frequently upregulated in cancer patients. This study aims to demonstrate the hypothesis that arecoline could induce the secretion of mitochondrial (mt) DNA D-loop...
2.
Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend?
Kuo C, Babuharisankar A, Lin Y, Lien H, Lo Y, Chou H, et al.
J Biomed Sci
. 2022 Sep;
29(1):74.
PMID: 36154922
The major concept of "oxidative stress" is an excess elevated level of reactive oxygen species (ROS) which are generated from vigorous metabolism and consumption of oxygen. The precise harmonization of...
3.
Wang Z, Lo I, Lin K, Cheng A, Zadeh S, Huang Y, et al.
Appl Environ Microbiol
. 2022 Aug;
88(17):e0080622.
PMID: 36000868
Albofungin, a hexacyclic aromatic natural product, exhibits broad-spectrum antimicrobial activity. Its biosynthesis, regulation, and resistance remain elusive. Here, we report the albofungin () biosynthetic gene cluster (BGC) from its producing...
4.
Cheng A, Cheng L, Kuo C, Lo Y, Chou H, Chen C, et al.
J Immunother Cancer
. 2020 Dec;
8(2).
PMID: 33268351
Background: Mitochondrial Lon is a chaperone and DNA-binding protein that functions in protein quality control and stress response pathways. The level of Lon regulates mitochondrial DNA (mtDNA) metabolism and the...
5.
Kuo C, Chou H, Chiu Y, Cheng A, Fan C, Chang Y, et al.
Cancer Lett
. 2020 Jan;
474:138-150.
PMID: 31987921
Mitochondrial Lon is a chaperone protein whose upregulation increases the production of mitochondrial reactive oxygen species (ROS). However, there is a lack of information in detail on how mitochondrial Lon...
6.
Fan C, Chen C, Chou C, Kao T, Cheng A, Lee A, et al.
J Clin Lab Anal
. 2019 Nov;
34(4):e23110.
PMID: 31733007
Background: Despite having chronic gastritis, most people infected by Helicobacter pylori (H. pylori) are asymptomatic and have no specific clinical signs and symptoms. H. pylori infection can be diagnosed by...
7.
Cheng A, Lo Y, Lin Y, Tang T, Hsu C, Hsu J, et al.
EBioMedicine
. 2018 Oct;
36:241-251.
PMID: 30293817
Background: Cdc7-Dbf4 is a conserved serine/threonine kinase that plays an important role in initiation of DNA replication and DNA damage tolerance in eukaryotic cells. Cdc7 has been found overexpressed in...
8.
Sung Y, Kao T, Kuo C, Fan C, Cheng A, Fang W, et al.
Cell Death Dis
. 2018 Jun;
9(6):697.
PMID: 29899330
Mitochondrial Lon is a multi-function matrix protease with chaperone activity. However, little literature has been undertaken into detailed investigations on how Lon regulates apoptosis through its chaperone activity. Accumulating evidences...
9.
Cheng A, Fan C, Lo Y, Kuo C, Wang H, Lien I, et al.
Sci Rep
. 2017 Dec;
7(1):17024.
PMID: 29209046
Cdc7-Dbf4 kinase plays a key role in the initiation of DNA replication and contributes to the replication stress in cancer. The activity of human Cdc7-Dbf4 kinase remains active and acts...
10.
Cheng A, Jiang S, Fan C, Lo Y, Kuo C, Chen C, et al.
Cancer Lett
. 2013 May;
337(2):218-25.
PMID: 23684929
Cdc7-Dbf4 kinase (Dbf4-dependent kinase, DDK) is an essential factor of DNA replication and DNA damage response (DDR), which is associated with tumorigenesis. However, Cdc7 expression has never been associated to...