Amy W Strilchuk
Overview
Explore the profile of Amy W Strilchuk including associated specialties, affiliations and a list of published articles.
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7
Citations
71
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Recent Articles
1.
Strilchuk A, Hur W, Batty P, Sang Y, Abrahams S, Yong A, et al.
Sci Transl Med
. 2024 Feb;
16(735):eadh0027.
PMID: 38381848
Antifibrinolytic drugs are used extensively for on-demand treatment of severe acute bleeding. Controlling fibrinolysis may also be an effective strategy to prevent or lessen chronic recurring bleeding in bleeding disorders...
2.
Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells
Ferraresso F, Strilchuk A, Juang L, Poole L, Luyendyk J, Kastrup C
Mol Pharm
. 2022 Jun;
19(7):2175-2182.
PMID: 35642083
Ionizable cationic lipids are essential for efficient delivery of RNA by lipid nanoparticles (LNPs). DLin-MC3-DMA (MC3), ALC-0315, and SM-102 are the only ionizable cationic lipids currently clinically approved for RNA...
3.
Juang L, Hur W, Silva L, Strilchuk A, Francisco B, Leung J, et al.
Blood
. 2021 Dec;
139(9):1302-1311.
PMID: 34958662
Fibrinogen plays a pathologic role in multiple diseases. It contributes to thrombosis and modifies inflammatory and immune responses, supported by studies in mice expressing fibrinogen variants with altered function or...
4.
Cau M, Strilchuk A, Kastrup C
J Thromb Haemost
. 2021 Mar;
19(4):887-891.
PMID: 33694243
No abstract available.
5.
Mazinani N, Strilchuk A, Baylis J, Hur W, Jefferies W, Kastrup C
Res Pract Thromb Haemost
. 2020 Jul;
4(5):823-828.
PMID: 32685890
Background: Amyloid precursor protein (APP) is highly expressed in platelets. APP is the precursor to amyloid beta (Aβ) peptides that accumulate in cerebral amyloid angiopathy and plaques in Alzheimer disease....
6.
Strilchuk A, Meixner S, Leung J, Safikhan N, Kulkarni J, Russell H, et al.
Blood
. 2020 Jul;
136(25):2946-2954.
PMID: 32678423
The activated form of coagulation factor XIII (FXIII-A2B2), FXIII-A*, is a hemostatic enzyme essential for inhibiting fibrinolysis by irreversibly crosslinking fibrin and antifibrinolytic proteins. Despite its importance, there are no...
7.
Manczyk N, Veggiani G, Teyra J, Strilchuk A, Sidhu S, Sicheri F
Sci Rep
. 2019 Mar;
9(1):4119.
PMID: 30858488
USP37 is a deubiquitinase (DUB) with roles in the regulation of DNA damage repair and the cohesion of sister chromatids during mitosis. USP37 contains a unique insert of three ubiquitin...