Amit Choudhary
Overview
Explore the profile of Amit Choudhary including associated specialties, affiliations and a list of published articles.
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81
Citations
1252
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Recent Articles
1.
Ramesh R, Aggarwal V, Choudhary A, Basu D, Nair N, Ganesan P, et al.
Asian Pac J Cancer Prev
. 2024 Sep;
25(9):3229-3237.
PMID: 39342602
Objective: To study the kinetics of blood count nadir and time to recovery and find its association with clinical outcomes in a cohort of Acute Lymphoblastic Leukemia (ALL). Methods: Data...
2.
Mercer J, DeCarlo S, Roy Burman S, Sreekanth V, Nelson A, Hunkeler M, et al.
Science
. 2024 Mar;
383(6688):eadk4422.
PMID: 38484051
Conditional protein degradation tags (degrons) are usually >100 amino acids long or are triggered by small molecules with substantial off-target effects, thwarting their use as specific modulators of endogenous protein...
3.
Shukla S, Sachan V, Sinha A, Pandey S, Rao G, Shah M, et al.
Sci Rep
. 2024 Feb;
14(1):3422.
PMID: 38341483
Biosensor nodes of a wireless body area network (WBAN) transmit physiological parameter data to a central hub node, spending a substantial portion of their energy. Therefore, it is crucial to...
4.
Choudhary A, Goodman C
Biochemistry
. 2023 Dec;
62(24):3453-3454.
PMID: 38111351
No abstract available.
5.
Nguyen T, Sreekanth V, Deb A, Kokkonda P, Tiwari P, Donovan K, et al.
Nat Chem
. 2023 Dec;
16(2):218-228.
PMID: 38110475
Proteolysis-targeting chimeras (PROTACs) are molecules that induce proximity between target proteins and E3 ligases triggering target protein degradation. Pomalidomide, a widely used E3 ligase recruiter in PROTACs, can independently degrade...
6.
Gibson W, Sadagopan A, Shoba V, Choudhary A, Meyerson M, Schreiber S
J Am Chem Soc
. 2023 Nov;
145(48):26028-26037.
PMID: 37992275
The aberrant localization of proteins in cells is a key factor in the development of various diseases, including cancer and neurodegenerative disease. To better understand and potentially manipulate protein localization...
7.
Gupta A, Kapoor A, Mishra B, Kashyap L, Choudhary A, Singh A, et al.
South Asian J Cancer
. 2023 Nov;
12(2):153-158.
PMID: 37969673
Anuj Gupta The aim of this study was to do a retrospective analysis of patients of gestational trophoblastic neoplasia (GTN) treated at our center concerning their clinical features and treatment...
8.
Kahraman S, Shibue K, De Jesus D, Kim H, Hu J, Manna D, et al.
Elife
. 2023 Sep;
12.
PMID: 37732504
Pancreatic α-cells secrete glucagon, an insulin counter-regulatory peptide hormone critical for the maintenance of glucose homeostasis. Investigation of the function of human α-cells remains a challenge due to the lack...
9.
Pergu R, Shoba V, Chaudhary S, Munkanatta Godage D, Deb A, Singha S, et al.
ACS Cent Sci
. 2023 Aug;
9(8):1558-1566.
PMID: 37637727
Chimeric small molecules that induce post-translational modification (PTM) on a target protein by bringing it into proximity to a PTM-inducing enzyme are furnishing novel modalities to perturb protein function. Despite...
10.
Singh S, Tian W, Severance Z, Chaudhary S, Anokhina V, Mondal B, et al.
Chem Soc Rev
. 2023 Jul;
52(16):5485-5515.
PMID: 37477631
Living systems use proximity to regulate biochemical processes. Inspired by this phenomenon, bifunctional modalities that induce proximity have been developed to redirect cellular processes. An emerging example of this class...