Jonathan D Schertzer
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Explore the profile of Jonathan D Schertzer including associated specialties, affiliations and a list of published articles.
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126
Citations
5637
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Recent Articles
1.
Conn M, DeJong E, Marko D, Fayyazi R, Kukje Zada D, Foley K, et al.
Am J Physiol Cell Physiol
. 2025 Feb;
328(3):C887-C894.
PMID: 39925101
Chronic low-level inflammation or "inflammaging" is hypothesized to contribute to sarcopenia and frailty. Resident microbiota are thought to promote inflammaging, frailty, and loss of skeletal muscle mass. We tested immunity...
2.
Barra N, Fang H, Bhatwa A, Schmidt A, Syed S, Steinberg G, et al.
Am J Physiol Endocrinol Metab
. 2025 Jan;
328(3):E337-E353.
PMID: 39871724
Metabolic disease is rising along with both global industrialization and the use of new commercial, agricultural, and industrial chemicals and food additives. Exposure to these compounds may contribute to aspects...
3.
Conn M, Marko D, Schertzer J
Physiology (Bethesda)
. 2024 Dec;
PMID: 39718947
No abstract available.
4.
Rodrigues E-Lacerda R, Barra N, Fang H, Anhe G, Schertzer J
iScience
. 2024 Nov;
27(11):111130.
PMID: 39507249
Obesity is associated with compartmentalized changes in immune responses that can be protective or pathogenic. It has been proposed that obesity-related changes in the microbiota influence allergic lung inflammation. We...
5.
Fang H, Rodrigues E-Lacerda R, Barra N, Kukje Zada D, Robin N, Mehra A, et al.
Endocr Rev
. 2024 Sep;
46(1):60-79.
PMID: 39235984
The gut microbiota influences aspects of metabolic disease, including tissue inflammation, adiposity, blood glucose, insulin, and endocrine control of metabolism. Prebiotics or probiotics are often sought to combat metabolic disease....
6.
Conn M, Marko D, Schertzer J
Am J Physiol Endocrinol Metab
. 2024 Aug;
327(4):E470-E477.
PMID: 39196802
Obesity and type 2 diabetes (T2D) are associated with metabolic inflexibility, characterized by an impaired ability to switch between substrate storage and utilization pathways. Metabolic inflexibility during obesity is typified...
7.
Chan D, Barra N, Fang H, Rodrigues E-Lacerda R, Schertzer J
Am J Physiol Endocrinol Metab
. 2024 Jul;
327(3):E271-E278.
PMID: 39017678
Obesity is associated with metabolic inflammation, which can contribute to insulin resistance, higher blood glucose, and higher insulin indicative of prediabetes progression. The nucleotide-binding oligomerization domain-like receptor family pyrin domain...
8.
Bakhshandeh F, Zheng H, Barra N, Sadeghzadeh S, Ausri I, Sen P, et al.
Adv Mater
. 2024 May;
36(35):e2313743.
PMID: 38752744
Continuous monitoring of clinically relevant biomarkers within the interstitial fluid (ISF) using microneedle (MN)-based assays, has the potential to transform healthcare. This study introduces the Wearable Aptalyzer, an integrated system...
9.
Marko D, Conn M, Schertzer J
Trends Endocrinol Metab
. 2024 May;
35(9):821-833.
PMID: 38719726
Intermittent fasting (IF) modifies cell- and tissue-specific immunometabolic responses that dictate metabolic flexibility and inflammation during obesity and type 2 diabetes (T2D). Fasting forces periods of metabolic flexibility and necessitates...
10.
Ribeiro T, Breznik J, Kennedy K, Yeo E, Kennelly B, Jazwiec P, et al.
PLoS One
. 2023 Aug;
18(8):e0284972.
PMID: 37549142
It is clear that the gastrointestinal tract influences metabolism and immune function. Most studies to date have used male test subjects, with a focus on effects of obesity and dietary...