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Amber M Bradley

Explore the profile of Amber M Bradley including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 183
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Recent Articles
1.
Wright J, Eskaros A, Windon A, Bottino R, Jenkins R, Bradley A, et al.
Diabetes . 2023 Oct; 73(7):1140-1152. PMID: 37881846
Article Highlights:
2.
Richardson T, Saunders D, Haliyur R, Shrestha S, Cartailler J, Reinert R, et al.
Am J Physiol Endocrinol Metab . 2023 Jan; 324(3):E251-E267. PMID: 36696598
The autonomic nervous system regulates pancreatic function. Islet capillaries are essential for the extension of axonal projections into islets, and both of these structures are important for appropriate islet hormone...
3.
Murphy M, Kumar P, Bradley A, Barton C, Deweese J, Mercer S
Bioorg Med Chem . 2020 Oct; 28(22):115773. PMID: 33035756
Etoposide is a widely-used anticancer agent that targets human type II topoisomerases. Evidence suggests that metabolism of etoposide in myeloid progenitor cells is associated with translocations involved in leukemia development....
4.
McDonough E, Barrett C, Parang B, Mittal M, Smith J, Bradley A, et al.
JCI Insight . 2017 Aug; 2(16). PMID: 28814670
MTG16 is a member of the myeloid translocation gene (MTG) family of transcriptional corepressors. While MTGs were originally identified in chromosomal translocations in acute myeloid leukemia, recent studies have uncovered...
5.
Barrett C, K Reddy V, Short S, Motley A, Lintel M, Bradley A, et al.
J Clin Invest . 2015 Jun; 125(7):2646-60. PMID: 26053663
Patients with inflammatory bowel disease are at increased risk for colon cancer due to augmented oxidative stress. These patients also have compromised antioxidant defenses as the result of nutritional deficiencies....
6.
Barrett C, Singh K, Motley A, Lintel M, Matafonova E, Bradley A, et al.
PLoS One . 2013 Jul; 8(7):e67845. PMID: 23861820
Selenium (Se) is an essential micronutrient that exerts its functions via selenoproteins. Little is known about the role of Se in inflammatory bowel disease (IBD). Epidemiological studies have inversely correlated...
7.
Hartman J, Bradley A, Laddusaw R, Perry Jr M, Miller G
Arch Biochem Biophys . 2013 Jul; 537(1):12-20. PMID: 23811196
CYP2E1 plays a critical role in detoxification and carcinogenic activation of drugs, pollutants, and dietary compounds; however, these metabolic processes can involve poorly characterized cooperative interactions that compromise the ability...
8.
Bradley A, Devine M, DeRemer D
Am J Health Syst Pharm . 2013 Mar; 70(7):589-97. PMID: 23515511
Purpose: The pharmacology, pharmacokinetics, clinical efficacy, and safety and tolerability of brentuximab vedotin are reviewed. Summary: Brentuximab vedotin is a potent antibody-drug conjugate composed of the monoclonal antibody cAC10, which...
9.
Bradley A, Valgus J, Bernard S
J Palliat Med . 2013 Mar; 16(4):409-11. PMID: 23477303
Background: Converting between the various opioid agents continues to be challenge for many practitioners. Specifically, variable recommendations for converting to the transdermal fentanyl patch may lead to confusion among clinicians...
10.
Bradley A, Deal A, Buie L, van Deventer H
Pharmacotherapy . 2012 Dec; 32(12):1070-7. PMID: 23208834
Study Objective: To determine whether granulocyte colony-stimulating factor (G-CSF) prophylaxis after consolidation with high- or intermediate-dose cytarabine (H/IDAC) for treatment of acute myeloid leukemia (AML) reduces the frequency of neutropenia-associated...