Amanda E Brandon
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Explore the profile of Amanda E Brandon including associated specialties, affiliations and a list of published articles.
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39
Citations
859
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Recent Articles
1.
Small L, Nguyen T, Larance M, Saunders D, Hoy A, Schmitz-Peiffer C, et al.
J Lipid Res
. 2024 Nov;
65(12):100687.
PMID: 39490929
De novo lipogenesis (DNL) has been implicated in the development and progression of liver steatosis. Hepatic DNL is strongly influenced by dietary macronutrient composition with diets high in carbohydrate increasing...
2.
Van Woerkom A, Harney D, Nagarajan S, Hakeem-Sanni M, Lin J, Hooke M, et al.
Am J Physiol Endocrinol Metab
. 2024 Apr;
326(6):E842-E855.
PMID: 38656127
Fatty liver is characterized by the expansion of lipid droplets (LDs) and is associated with the development of many metabolic diseases. We assessed the morphology of hepatic LDs and performed...
3.
Yau B, Naghiloo S, Diaz-Vegas A, Carr A, van Gerwen J, Needham E, et al.
iScience
. 2024 Jan;
27(1):108707.
PMID: 38188515
[This corrects the article DOI: 10.1016/j.isci.2021.103099.].
4.
Osborne B, Wright L, Brandon A, Stuart E, Small L, Hoeks J, et al.
J Endocrinol
. 2023 Jun;
258(3).
PMID: 37335200
Reduced expression of the NAD+-dependent deacetylase, SIRT3, has been associated with insulin resistance and metabolic dysfunction in humans and rodents. In this study, we investigated whether specific overexpression of SIRT3...
5.
Brandon A, Small L, Nguyen T, Suryana E, Gong H, Yassmin C, et al.
Elife
. 2022 Nov;
11.
PMID: 36394259
Obesity is generally associated with insulin resistance in liver and muscle and increased risk of developing type 2 diabetes, however there is a population of obese people that remain insulin...
6.
Campbell G, Lucic Fisher S, Brandon A, Senior A, Bell-Anderson K
Front Nutr
. 2022 Aug;
9:917880.
PMID: 35942169
Objectives: glycemia is an important determinant of fetal growth. Women with gestational diabetes are more likely to deliver large-for-gestational age babies that are at increased risk for obesity. The maternal...
7.
Nelson M, Madsen S, Cooke K, Fritzen A, Thorius I, Masson S, et al.
Cell Metab
. 2022 Jan;
34(2):227-239.e6.
PMID: 35021042
Skeletal muscle and adipose tissue insulin resistance are major drivers of metabolic disease. To uncover pathways involved in insulin resistance, specifically in these tissues, we leveraged the metabolic diversity of...
8.
Le Couteur D, Solon-Biet S, Parker B, Pulpitel T, Brandon A, Hunt N, et al.
Cell Metab
. 2021 Nov;
33(12):2367-2379.e4.
PMID: 34767745
Nutrient sensing pathways influence metabolic health and aging, offering the possibility that diet might be used therapeutically, alone or with drugs targeting these pathways. We used the Geometric Framework for...
9.
Yau B, Naghiloo S, Diaz-Vegas A, Carr A, van Gerwen J, Needham E, et al.
iScience
. 2021 Oct;
24(10):103099.
PMID: 34622154
Pancreatic islets are essential for maintaining physiological blood glucose levels, and declining islet function is a hallmark of type 2 diabetes. We employ mass spectrometry-based proteomics to systematically analyze islets...
10.
Wali J, Milner A, Luk A, Pulpitel T, Dodgson T, Facey H, et al.
Nat Metab
. 2021 Jun;
3(6):810-828.
PMID: 34099926
Reduced protein intake, through dilution with carbohydrate, extends lifespan and improves mid-life metabolic health in animal models. However, with transition to industrialised food systems, reduced dietary protein is associated with...