Alvaro F Magalhaes
Overview
Explore the profile of Alvaro F Magalhaes including associated specialties, affiliations and a list of published articles.
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6
Citations
46
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Recent Articles
1.
Ghoshal A, Magalhaes A, Asressu K, Hossain M, Todd M, Willson T
Pharmaceuticals (Basel)
. 2024 Jul;
17(7).
PMID: 39065687
Optimized syntheses of ()-5-(2-ethoxyphenyl)--(3-(methylsulfonyl)allyl)-1-pyrazole-3-carboxamide (RA-0002034, ), a promising antiviral covalent cysteine protease inhibitor lead, were developed. The syntheses avoid the contamination of with the inactive cyclic dihydropyrazolo[1,5-]pyrazin-4(5)-one , which is...
2.
Magalhaes A, Powner M
Chem Commun (Camb)
. 2022 Nov;
58(97):13519-13522.
PMID: 36398592
Proline and phosphate promote a near-quantitative aldol reaction between glycolaldehyde phosphate and formaldehyde at neutral pH in water. Our results demonstrate the important role of general acid-base catalysis in water...
3.
Loureiro D, Magalhaes A, Soares J, Pinto J, Azevedo C, Vieira S, et al.
ChemMedChem
. 2020 Mar;
15(9):749-755.
PMID: 32162478
Natural products have always been an important source of new hits and leads in drug discovery, with the marine environment being regarded as a significant source of novel and exquisite...
4.
Loureiro D, Soares J, Costa J, Magalhaes A, Azevedo C, Pinto M, et al.
Molecules
. 2019 Jan;
24(2).
PMID: 30634698
Marine organisms represent almost half of total biodiversity and are a very important source of new bioactive substances. Within the varied biological activities found in marine products, their antimicrobial activity...
5.
Magalhaes A, Graca V, Calhelha R, Ferreira Machado I, Vieira Ferreira L, Ferreira I, et al.
Photochem Photobiol Sci
. 2018 Oct;
18(2):336-342.
PMID: 30310913
Squaraine dyes have recently attracted interest as potential second generation photosensitizers for photodynamic therapy. Several cationic aminosquaraine dyes bearing benzoselenazole terminal nuclei were synthezised and their cytotoxic activity was tested...
6.
Magalhaes A, Graca V, Calhelha R, Ferreira I, Santos P
Bioorg Med Chem Lett
. 2017 Aug;
27(18):4467-4470.
PMID: 28807437
The synthesis of several aminosquaraine cationic dyes displaying strong absorption within the so-called phototherapeutic window (650-850nm) is described. Their cytotoxicity, under dark and illuminated conditions, was tested against several human...