Alonso P Moreno
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Explore the profile of Alonso P Moreno including associated specialties, affiliations and a list of published articles.
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24
Citations
611
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Recent Articles
1.
Chaudhari S, Sharma K, Marchetto J, Hydren J, Burton B, Moreno A
Bone Rep
. 2021 Oct;
15:101141.
PMID: 34692946
Background: Bone remodeling is a lifelong process that ranges from orthodontic tooth movement/alignment to bone damage/healing, to overall bone health. Osteoprotegerin (OPG) and transforming growth factor β1 (TGF-β1) are secreted...
2.
Garciarena C, Malik A, Swietach P, Moreno A, Vaughan-Jones R
FASEB J
. 2017 Nov;
32(4):1969-1981.
PMID: 29183963
Most mammalian cells can intercommunicate via connexin-assembled, gap-junctional channels. To regulate signal transmission, connexin (Cx) channel permeability must respond dynamically to physiological and pathophysiological stimuli. One key stimulus is intracellular...
3.
Zhong G, Akoum N, Appadurai D, Hayrapetyan V, Ahmed O, Martinez A, et al.
Front Physiol
. 2017 Jun;
8:346.
PMID: 28611680
In cardiac tissues, the expression of multiple connexins (Cx40, Cx43, Cx45, and Cx30.2) is a requirement for proper development and function. Gap junctions formed by these connexins have distinct permeability...
4.
Mondal A, Sachse F, Moreno A
Front Physiol
. 2017 Apr;
8:206.
PMID: 28428758
Gap junction channels play a vital role in intercellular communication by connecting cytoplasm of adjoined cells through arrays of channel-pores formed at the common membrane junction. Their structure and properties...
5.
Computational simulations of asymmetric fluxes of large molecules through gap junction channel pores
Mondal A, Appadurai D, Akoum N, Sachse F, Moreno A
J Theor Biol
. 2016 Nov;
412:61-73.
PMID: 27590324
Gap junction channels are formed out of connexin isoforms, which enable molecule and ion selective diffusion amongst neighboring cells. HeLa cells expressing distinct connexins (Cx) allow the formation of heterotypic...
6.
Winters A, Bou-Ghannam S, Thorp H, Hawayek J, Atkinson D, Bartlett C, et al.
Cell Transplant
. 2016 May;
25(9):1591-1607.
PMID: 27165370
The development of cell- and gene-based strategies for regenerative medicine offers a therapeutic option for the repair and potential regeneration of damaged cardiac tissue post-myocardial infarction (MI). Human umbilical cord...
7.
Holt-Casper D, Theisen J, Moreno A, Warren M, Silva F, Grainger D, et al.
J Transl Med
. 2015 Jun;
13:194.
PMID: 26084398
Rationale: Myocardial infarction (MI) results in damaged heart tissue which can progress to severely reduce cardiac function, leading to death. Recent studies have injected dissociated, suspended cardiac cells into coronary...
8.
Riedel M, Jou C, Lai S, Lux R, Moreno A, Spitzer K, et al.
Stem Cell Reports
. 2014 Jul;
3(1):131-41.
PMID: 25068127
Advances in induced pluripotent stem cell (iPSC) technology have set the stage for routine derivation of patient- and disease-specific human iPSC-cardiomyocyte (CM) models for preclinical drug screening and personalized medicine...
9.
Sohn K, Wende A, Abel E, Moreno A, Sachse F, Punske B
Exp Physiol
. 2012 Nov;
98(3):746-57.
PMID: 23180812
Insulin resistance, which characterizes type 2 diabetes, is associated with reduced translocation of glucose transporter 4 (GLUT4) to the plasma membrane following insulin stimulation, and diabetic patients with insulin resistance...
10.
Larsen A, Sciuto K, Moreno A, Poelzing S
Heart Rhythm
. 2012 Apr;
9(9):1493-500.
PMID: 22537886
Background: Voltage-sensitive dyes are important tools for mapping electrical activity in the heart. However, little is known about the effects of voltage-sensitive dyes on cardiac electrophysiology. Objective: To test the...