Allison S Harney
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Explore the profile of Allison S Harney including associated specialties, affiliations and a list of published articles.
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24
Citations
1380
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Recent Articles
1.
Anastasiadou D, Couturier N, Goel S, Argyris D, Vodopyanov S, Rivera-Sanchez L, et al.
bioRxiv
. 2024 Oct;
PMID: 39464015
Although the CXCL12/CXCR4 pathway has been prior investigated for its prometastatic and immuno- suppressive roles in the tumor microenvironment, evidence on the spatiotemporal regulation of these hallmarks has been lacking....
2.
Surve C, Duran C, Ye X, Chen X, Lin Y, Harney A, et al.
bioRxiv
. 2024 Jan;
PMID: 38260319
Tumor cell intravasation is essential for metastatic dissemination, but its exact mechanism is incompletely understood. We have previously shown that in breast cancer, the direct and stable association of a...
3.
Drilon A, Sharma M, Johnson M, Yap T, Gadgeel S, Nepert D, et al.
Cancer Discov
. 2023 Jun;
13(8):1789-1801.
PMID: 37269335
Significance: PF-07284892-targeted therapy combinations overcame bypass-signaling-mediated resistance in a clinical setting in which neither component was active on its own. This provides proof of concept of the utility of SHP2...
4.
Karagiannis G, Bianchi A, Sanchez L, Ambadipudi K, Cui M, Anampa J, et al.
NPJ Breast Cancer
. 2022 Sep;
8(1):101.
PMID: 36056005
Metastatic dissemination in breast cancer is regulated by specialized intravasation sites called "tumor microenvironment of metastasis" (TMEM) doorways, composed of a tumor cell expressing the actin-regulatory protein Mena, a perivascular...
5.
Schuler M, Zimmer L, Kim K, Sosman J, Ascierto P, Postow M, et al.
Clin Cancer Res
. 2022 Mar;
28(14):3002-3010.
PMID: 35294522
Purpose: Enhanced MAPK pathway signaling and cell-cycle checkpoint dysregulation are frequent in NRAS-mutant melanoma and, as such, the regimen of the MEK inhibitor binimetinib and the selective CDK4/6 inhibitor ribociclib...
6.
Liu X, Taftaf R, Kawaguchi M, Chang Y, Chen W, Entenberg D, et al.
Cancer Discov
. 2018 Oct;
9(1):96-113.
PMID: 30361447
Circulating tumor cells (CTC) seed cancer metastases; however, the underlying cellular and molecular mechanisms remain unclear. CTC clusters were less frequently detected but more metastatic than single CTCs of patients...
7.
Arwert E, Harney A, Entenberg D, Wang Y, Sahai E, Pollard J, et al.
Cell Rep
. 2018 May;
23(5):1239-1248.
PMID: 29719241
Tumor-associated macrophages (TAMs) are critical for tumor metastasis. Two TAM subsets support cancer cell intravasation: migratory macrophages guide cancer cells toward blood vessels, where sessile perivascular macrophages assist their entry...
8.
Harney A, Karagiannis G, Pignatelli J, Smith B, Kadioglu E, Wise S, et al.
Mol Cancer Ther
. 2017 Aug;
16(11):2486-2501.
PMID: 28838996
Tumor-infiltrating myeloid cells promote tumor progression by mediating angiogenesis, tumor cell intravasation, and metastasis, which can offset the effects of chemotherapy, radiation, and antiangiogenic therapy. Here, we show that the...
9.
Karagiannis G, Pastoriza J, Wang Y, Harney A, Entenberg D, Pignatelli J, et al.
Sci Transl Med
. 2017 Jul;
9(397).
PMID: 28679654
Breast cancer cells disseminate through TIE2/MENA/MENA-dependent cancer cell intravasation sites, called tumor microenvironment of metastasis (TMEM), which are clinically validated as prognostic markers of metastasis in breast cancer patients. Using...
10.
Lewis C, Harney A, Pollard J
Cancer Cell
. 2016 Aug;
30(2):365.
PMID: 27505682
No abstract available.