Alina Zamoshnikova
Overview
Explore the profile of Alina Zamoshnikova including associated specialties, affiliations and a list of published articles.
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7
Citations
502
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0
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Recent Articles
1.
Coombs J, Zamoshnikova A, Holley C, Maddugoda M, Teo D, Chauvin C, et al.
Sci Signal
. 2024 Jan;
17(820):eabg8145.
PMID: 38261657
Inflammasomes are multiprotein complexes that drive inflammation and contribute to protective immunity against pathogens and immune pathology in autoinflammatory diseases. Inflammasomes assemble when an inflammasome scaffold protein senses an activating...
2.
Tran T, Mathmann C, Gatica-Andrades M, Rollo R, Oelker M, Ljungberg J, et al.
PLoS Pathog
. 2022 Jan;
18(1):e1010166.
PMID: 35007292
A hallmark of Listeria (L.) monocytogenes pathogenesis is bacterial escape from maturing entry vacuoles, which is required for rapid bacterial replication in the host cell cytoplasm and cell-to-cell spread. The...
3.
Dominguez Cadena L, Schultz T, Zamoshnikova A, Donovan M, Mathmann C, Yu C, et al.
Immunol Cell Biol
. 2021 Sep;
99(10):1067-1076.
PMID: 34555867
The proinflammatory cytokine tumor necrosis factor (TNF) plays a central role in the host control of mycobacterial infections. Expression and release of TNF are tightly regulated, yet the molecular mechanisms...
4.
Coll R, Hill J, Day C, Zamoshnikova A, Boucher D, Massey N, et al.
Nat Chem Biol
. 2019 May;
15(6):556-559.
PMID: 31086327
Inhibition of the NLRP3 inflammasome is a promising strategy for the development of new treatments for inflammatory diseases. MCC950 is a potent and specific small-molecule inhibitor of the NLRP3 pathway,...
5.
Sester D, Zamoshnikova A, Thygesen S, Vajjhala P, Cridland S, Schroder K, et al.
Curr Protoc Immunol
. 2016 Aug;
114:14.40.1-14.40.29.
PMID: 27479658
Inflammasomes are large protein complexes formed in response to cellular stresses that are platforms for recruitment and activation of caspase 1. Central to most inflammasome functions is the adapter molecule...
6.
Zamoshnikova A, Gross C, Schuster S, Chen K, Wilson A, Tacchini-Cottier F, et al.
Immunobiology
. 2015 Oct;
221(2):341-6.
PMID: 26514298
NOD-like receptors (NLR) are a family of cytosolic pattern recognition receptors that include many key drivers of innate immune responses. NLRP12 is an emerging member of the NLR family that...
7.
Schroder K, Sagulenko V, Zamoshnikova A, Richards A, Cridland J, Irvine K, et al.
Immunobiology
. 2012 Aug;
217(12):1325-9.
PMID: 22898390
Macrophage pre-treatment with bacterial lipopolysaccharide (LPS) boosts subsequent activation of the NLRP3 inflammasome, which controls caspase-1-dependent pro-inflammatory cytokine maturation. Previous work has attributed this phenomenon (known as LPS 'priming') to...