Alina Renz
Overview
Explore the profile of Alina Renz including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
347
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Recent Articles
1.
Leonidou N, Fritze E, Renz A, Drager A
Bioinformatics
. 2023 Jul;
39(7).
PMID: 37449910
Motivation: The number and size of computational models in biology have drastically increased over the past years and continue to grow. Modeled networks are becoming more complex, and reconstructing them...
2.
Leonidou N, Renz A, Mostolizadeh R, Drager A
PLoS Comput Biol
. 2023 Mar;
19(3):e1010903.
PMID: 36952396
COVID-19 is one of the deadliest respiratory diseases, and its emergence caught the pharmaceutical industry off guard. While vaccines have been rapidly developed, treatment options for infected people remain scarce,...
3.
Dahal S, Renz A, Drager A, Yang L
Commun Biol
. 2023 Feb;
6(1):165.
PMID: 36765199
Pseudomonas aeruginosa is one of the leading causes of hospital-acquired infections. To decipher the metabolic mechanisms associated with virulence and antibiotic resistance, we have developed an updated genome-scale model (GEM)...
4.
Geissert J, Bohn E, Mostolizadeh R, Drager A, Autenrieth I, Beier S, et al.
Biology (Basel)
. 2022 Feb;
11(2).
PMID: 35205164
The complex interplay of a pathogen with its virulence and fitness factors, the host's immune response, and the endogenous microbiome determine the course and outcome of gastrointestinal infection. The expansion...
5.
Ostaszewski M, Niarakis A, Mazein A, Kuperstein I, Phair R, Orta-Resendiz A, et al.
Mol Syst Biol
. 2021 Dec;
17(12):e10851.
PMID: 34939300
No abstract available.
6.
Feierabend M, Renz A, Zelle E, Noh K, Wiechert W, Drager A
Front Microbiol
. 2021 Dec;
12:750206.
PMID: 34867870
belongs to the microbes of enormous biotechnological relevance. In particular, its strain ATCC 13032 is a widely used producer of L-amino acids at an industrial scale. Its apparent robustness also...
7.
Ostaszewski M, Niarakis A, Mazein A, Kuperstein I, Phair R, Orta-Resendiz A, et al.
Mol Syst Biol
. 2021 Oct;
17(10):e10387.
PMID: 34664389
We need to effectively combine the knowledge from surging literature with complex datasets to propose mechanistic models of SARS-CoV-2 infection, improving data interpretation and predicting key targets of intervention. Here,...
8.
Payne D, Renz A, Dunphy L, Lewis T, Drager A, Papin J
NPJ Syst Biol Appl
. 2021 Oct;
7(1):37.
PMID: 34625561
Mucins are present in mucosal membranes throughout the body and play a key role in the microbe clearance and infection prevention. Understanding the metabolic responses of pathogens to mucins will...
9.
Renz A, Drager A
NPJ Syst Biol Appl
. 2021 Jun;
7(1):30.
PMID: 34188046
Staphylococcus aureus is a high-priority pathogen causing severe infections with high morbidity and mortality worldwide. Many S. aureus strains are methicillin-resistant (MRSA) or even multi-drug resistant. It is one of...
10.
Renz A, Widerspick L, Drager A
Genes (Basel)
. 2021 Jun;
12(6).
PMID: 34073716
The current SARS-CoV-2 pandemic is still threatening humankind. Despite first successes in vaccine development and approval, no antiviral treatment is available for COVID-19 patients. The success is further tarnished by...