Alice L-F Mui
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Explore the profile of Alice L-F Mui including associated specialties, affiliations and a list of published articles.
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19
Citations
355
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Recent Articles
1.
Chamberlain T, Cheung S, Yoon J, Ming-Lum A, Gardill B, Shakibakho S, et al.
iScience
. 2020 Aug;
23(8):101433.
PMID: 32823063
The anti-inflammatory actions of interleukin-10 (IL10) are thought to be mediated primarily by the STAT3 transcription factor, but pro-inflammatory cytokines such as interleukin-6 (IL6) also act through STAT3. We now...
2.
Samiea A, Yoon J, Ong C, Zoubeidi A, Chamberlain T, Mui A
Prostate Cancer
. 2020 Aug;
2020:5305306.
PMID: 32802517
Interleukin-10 (IL10) is best studied for its inhibitory action on immune cells and ability to suppress an antitumour immune response. But IL10 also exerts direct effects on nonimmune cells such...
3.
Yoon J, Wu M, Zhu T, Zhao H, Cheung S, Chamberlain T, et al.
PLoS One
. 2020 Apr;
15(4):e0231639.
PMID: 32324763
The anti-inflammatory cytokine interleukin-10 (IL10) is essential for attenuating inflammatory responses, which includes reducing the expression of pro-inflammatory microRNA-155 (miR155) in lipopolysaccharide (LPS) activated macrophages. miR155 enhances the expression of...
4.
Samiea A, Yoon J, Cheung S, Chamberlain T, Mui A
PLoS One
. 2020 Apr;
15(4):e0230427.
PMID: 32240179
Macrophage cells form part of our first line defense against pathogens. Macrophages become activated by microbial products such as lipopolysaccharide (LPS) to produce inflammatory mediators, such as TNFα and other...
5.
Peacock J, Takeuchi A, Hayashi N, Liu L, Tam K, Al Nakouzi N, et al.
EMBO Mol Med
. 2018 Jan;
10(2):219-238.
PMID: 29348142
Growth factor receptor tyrosine kinase (RTK) pathway activation is a key mechanism for mediating cancer growth, survival, and treatment resistance. Cognate ligands play crucial roles in autocrine or paracrine stimulation...
6.
Cheung S, Shakibakho S, So E, Mui A
J Vis Exp
. 2015 Jul;
(100):e52807.
PMID: 26132366
Transfection of desired genetic materials into cells is an inevitable procedure in biomedical research studies. While numerous methods have been described, certain types of cells are resistant to many of...
7.
Cheung S, So E, Chang D, Ming-Lum A, Mui A
PLoS One
. 2013 Aug;
8(8):e71336.
PMID: 23951138
The anti-inflammatory cytokine interleukin-10 (IL-10) is essential for attenuating the inflammatory response, which includes reducing the expression of pro-inflammatory microRNA-155 (miR-155) in lipopolysaccharide (LPS) activated macrophages. miR-155 enhances the expression...
8.
Chan C, Ming-Lum A, Golds G, Lee S, Anderson R, Mui A
J Biol Chem
. 2012 Sep;
287(45):38020-7.
PMID: 22955274
Production of the proinflammatory cytokine TNFα by activated macrophages is an important component of host defense. However, TNFα production must be tightly controlled to avoid pathological consequences. The anti-inflammatory cytokine...
9.
10.
Ming-Lum A, Shojania S, So E, McCarrell E, Shaw E, Vu D, et al.
FASEB J
. 2012 Jun;
26(8):3163-77.
PMID: 22651931
SH2 domain-containing inositol-5'-phosphatase-1 (SHIP1) inhibits inflammation by hydrolyzing phosphoinositide-3'-kinase generated membrane phosphatidylinositol-3,4,5-trisphosphate (PIP(3)). Bioinformatic analysis of SHIP1 from multiple species revealed a pleckstrin homololgy-related (PH-R) domain, which we hypothesize mediates...