Thomas C Chamberlain
Overview
Explore the profile of Thomas C Chamberlain including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
157
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0
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Recent Articles
1.
Islam H, Chamberlain T, Mui A, Little J
Front Immunol
. 2021 Jul;
12:677008.
PMID: 34234779
No abstract available.
2.
Chamberlain T, Cheung S, Yoon J, Ming-Lum A, Gardill B, Shakibakho S, et al.
iScience
. 2020 Aug;
23(8):101433.
PMID: 32823063
The anti-inflammatory actions of interleukin-10 (IL10) are thought to be mediated primarily by the STAT3 transcription factor, but pro-inflammatory cytokines such as interleukin-6 (IL6) also act through STAT3. We now...
3.
Samiea A, Yoon J, Ong C, Zoubeidi A, Chamberlain T, Mui A
Prostate Cancer
. 2020 Aug;
2020:5305306.
PMID: 32802517
Interleukin-10 (IL10) is best studied for its inhibitory action on immune cells and ability to suppress an antitumour immune response. But IL10 also exerts direct effects on nonimmune cells such...
4.
Yoon J, Wu M, Zhu T, Zhao H, Cheung S, Chamberlain T, et al.
PLoS One
. 2020 Apr;
15(4):e0231639.
PMID: 32324763
The anti-inflammatory cytokine interleukin-10 (IL10) is essential for attenuating inflammatory responses, which includes reducing the expression of pro-inflammatory microRNA-155 (miR155) in lipopolysaccharide (LPS) activated macrophages. miR155 enhances the expression of...
5.
Samiea A, Yoon J, Cheung S, Chamberlain T, Mui A
PLoS One
. 2020 Apr;
15(4):e0230427.
PMID: 32240179
Macrophage cells form part of our first line defense against pathogens. Macrophages become activated by microbial products such as lipopolysaccharide (LPS) to produce inflammatory mediators, such as TNFα and other...
6.
Nicoletti P, Aithal G, Chamberlain T, Coulthard S, AlShabeeb M, Grove J, et al.
Clin Pharmacol Ther
. 2019 Jan;
106(1):245-253.
PMID: 30661239
Some patients prescribed flucloxacillin (~ 0.01%) develop drug-induced liver injury (DILI). HLA-B*57:01 is an established genetic risk factor for flucloxacillin DILI. To consolidate this finding, identify additional genetic factors, and...