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Alice Chen-Plotkin

Explore the profile of Alice Chen-Plotkin including associated specialties, affiliations and a list of published articles. Areas
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Articles 71
Citations 4921
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Recent Articles
1.
Shaw L, Korecka M, Lee E, Cousins K, Vanderstichele H, Schindler S, et al.
Alzheimers Dement . 2024 Nov; 21(1):e14264. PMID: 39614747
Background: We describe the Alzheimer's Disease Neuroimaging Initiative (ADNI) Biomarker Core major activities from October 2004 to March 2024, including biobanking ADNI cerebrospinal fluid (CSF), plasma, and serum biofluid samples,...
2.
Wilson E, Umans J, Swarovski M, Minhas P, Midttun O, Ulvik A, et al.
Res Sq . 2024 Oct; PMID: 39399688
Parkinson's disease (PD) is a complex multisystem disorder clinically characterized by motor, non-motor, and premotor manifestations. Pathologically, PD involves neuronal loss in the substantia nigra, striatal dopamine deficiency, and accumulation...
3.
Shantaraman A, Dammer E, Ugochukwu O, Duong D, Yin L, Carter E, et al.
Mol Neurodegener . 2024 Oct; 19(1):71. PMID: 39394136
No abstract available.
4.
Jang Y, Oh S, Hall A, Zhang Z, Tropea T, Chen-Plotkin A, et al.
Clin Proteomics . 2024 Sep; 21(1):56. PMID: 39342078
Background: Progressive supranuclear palsy (PSP) is a neurodegenerative disorder often misdiagnosed as Parkinson's Disease (PD) due to shared symptoms. PSP is characterized by the accumulation of tau protein in specific...
5.
Hok-A-Hin Y, Vermunt L, Peeters C, van der Ende E, de Boer S, Meeter L, et al.
medRxiv . 2024 Sep; PMID: 39228745
Diagnosis of Frontotemporal dementia (FTD) and the specific underlying neuropathologies (frontotemporal lobar degeneration; FTLD- Tau and FTLD-TDP) is challenging, and thus fluid biomarkers are needed to improve diagnostic accuracy. We...
6.
Shantaraman A, Dammer E, Ugochukwu O, Duong D, Yin L, Carter E, et al.
Mol Neurodegener . 2024 Aug; 19(1):60. PMID: 39107789
Lewy body dementia (LBD), a class of disorders comprising Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB), features substantial clinical and pathological overlap with Alzheimer's disease (AD). The...
7.
Han N, Paul R, Bardakjian T, Kargilis D, Bradbury A, Chen-Plotkin A, et al.
JMIR Bioinform Biotechnol . 2024 Jun; 4:e45370. PMID: 38935961
Background: Genetic testing is essential to identify research participants for clinical trials enrolling people with Parkinson disease (PD) carrying a variant in the glucocerebrosidase (GBA) or leucine-rich repeat kinase 2...
8.
Brown C, Das S, Xie L, Nasrallah I, Detre J, Chen-Plotkin A, et al.
Alzheimers Dement . 2024 May; 20(6):4147-4158. PMID: 38747539
Introduction: Typical MRI measures of neurodegeneration have limited sensitivity in early disease stages. Diffusion MRI (dMRI) microstructural measures may allow for detection in preclinical stages. Methods: Participants had dMRI and...
9.
Cousins K, Phillips J, Das S, OBrien K, Tropea T, Chen-Plotkin A, et al.
Alzheimers Dement . 2024 Apr; 20(6):3889-3905. PMID: 38644682
Introduction: We investigate pathological correlates of plasma phosphorylated tau 181 (p-tau), glial fibrillary acidic protein (GFAP), and neurofilament light chain (NfL) across a clinically diverse spectrum of neurodegenerative disease, including...
10.
Reus L, Jansen I, Tijms B, Visser P, Tesi N, van der Lee S, et al.
Brain . 2024 Mar; 147(10):3522-3533. PMID: 38527854
Genome-wide association studies have successfully identified many genetic risk loci for dementia, but exact biological mechanisms through which genetic risk factors contribute to dementia remains unclear. Integrating CSF proteomic data...