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John Q Trojanowski

Explore the profile of John Q Trojanowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 880
Citations 92173
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Recent Articles
1.
Wang L, Hu W, Dong F, Sheng C, Wu J, Han Y, et al.
Geroscience . 2025 Jan; PMID: 39888585
Brain network dynamics have been extensively explored in patients with subjective cognitive decline (SCD). However, these studies are susceptible to individual differences, scanning parameters, and other confounding factors. Therefore, how...
2.
Shantaraman A, Dammer E, Ugochukwu O, Duong D, Yin L, Carter E, et al.
Mol Neurodegener . 2024 Oct; 19(1):71. PMID: 39394136
No abstract available.
3.
Khandelwal P, Duong M, Sadaghiani S, Lim S, Denning A, Chung E, et al.
Imaging Neurosci (Camb) . 2024 Sep; 2():1-30. PMID: 39301426
MRI allows brain anatomy to be examined at high resolution and to link pathology measures with morphometric measurements. However, automated segmentation methods for brain mapping in postmortem MRI are not...
4.
Rexach J, Cheng Y, Chen L, Polioudakis D, Lin L, Mitri V, et al.
Cell . 2024 Sep; 187(20):5753-5774.e28. PMID: 39265576
The development of successful therapeutics for dementias requires an understanding of their shared and distinct molecular features in the human brain. We performed single-nuclear RNA-seq and ATAC-seq in Alzheimer's disease...
5.
Shantaraman A, Dammer E, Ugochukwu O, Duong D, Yin L, Carter E, et al.
Mol Neurodegener . 2024 Aug; 19(1):60. PMID: 39107789
Lewy body dementia (LBD), a class of disorders comprising Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB), features substantial clinical and pathological overlap with Alzheimer's disease (AD). The...
6.
Pottier C, Kucukali F, Baker M, Batzler A, Jenkins G, van Blitterswijk M, et al.
medRxiv . 2024 Jul; PMID: 38978643
Frontotemporal lobar degeneration with neuronal inclusions of the TAR DNA-binding protein 43 (FTLD-TDP) is a fatal neurodegenerative disorder with only a limited number of risk loci identified. We report our...
7.
Henderson M, Sengupta M, Trojanowski J, Lee V
Acta Neuropathol Commun . 2024 Jun; 12(1):110. PMID: 38943188
No abstract available.
8.
Nazeen S, Wang X, Zielinski D, Lam I, Hallacli E, Xu P, et al.
bioRxiv . 2024 Mar; PMID: 38496508
Whether neurodegenerative diseases linked to misfolding of the same protein share genetic risk drivers or whether different protein-aggregation pathologies in neurodegeneration are mechanistically related remains uncertain. Conventional genetic analyses are...
9.
Xu H, Qiu Q, Hu P, Hoxha K, Jang E, OReilly M, et al.
Acta Neuropathol . 2024 Mar; 147(1):55. PMID: 38472475
Inclusions comprised of microtubule-associated protein tau (tau) are implicated in a group of neurodegenerative diseases, collectively known as tauopathies, that include Alzheimer's disease (AD). The spreading of misfolded tau "seeds"...
10.
Shantaraman A, Dammer E, Ugochukwu O, Duong D, Yin L, Carter E, et al.
bioRxiv . 2024 Feb; PMID: 38328211
Lewy body dementia (LBD), a class of disorders comprising Parkinson's disease dementia (PDD) and dementia with Lewy bodies (DLB), features substantial clinical and pathological overlap with Alzheimer's disease (AD). The...