Alfredo Ramos-Miguel
Overview
Explore the profile of Alfredo Ramos-Miguel including associated specialties, affiliations and a list of published articles.
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29
Citations
335
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Recent Articles
1.
Martinez-Peula O, Ramos-Miguel A, Muguruza C, Callado L, Meana J, Rivero G
J Neurosci Methods
. 2025 Jan;
416:110365.
PMID: 39832625
Background: Histone deacetylase (HDAC) density and activity are altered in different brain disorders. Antipsychotic drugs (APs) might modulate HDAC activity in brains of schizophrenia subjects. New Method: HDAC activity assay...
2.
Jones A, Ramos-Miguel A, Gicas K, Petyuk V, Leurgans S, De Jager P, et al.
Alzheimers Dement
. 2024 Oct;
20(11):8012-8027.
PMID: 39394857
Introduction: In the aging brain, cognitive abilities emerge from the coordination of complex pathways arising from a balance between protective lifestyle and environmental factors and accumulation of neuropathologies. Methods: As...
3.
Fernandez-Rhodes M, Lorca C, Lisa J, Batalla I, Ramos-Miguel A, Gallart-Palau X, et al.
Int J Mol Sci
. 2024 Jul;
25(13).
PMID: 39000260
Extracellular vesicles (EVs) constitute a sophisticated molecular exchange mechanism highly regarded for their potential as a next-generation platform for compound delivery. However, identifying sustainable and biologically safe sources of EVs...
4.
DelaCuesta-Barrutia J, Martinez-Peula O, Rivero G, Santas-Martin J, Munarriz-Cuezva E, Brocos-Mosquera I, et al.
Transl Psychiatry
. 2024 Feb;
14(1):113.
PMID: 38396013
Antipsychotic-induced low availability of group II metabotropic glutamate receptors (including mGluR and mGluR) in brains of schizophrenia patients may explain the limited efficacy of mGluR ligands in clinical trials. Studies...
5.
Martinez-Peula O, Morentin B, Callado L, Meana J, Rivero G, Ramos-Miguel A
J Psychiatry Neurosci
. 2024 Feb;
49(1):E35-E44.
PMID: 38302137
Background: Susceptibility to schizophrenia is determined by interactions between genes and environment, possibly via epigenetic mechanisms. Schizophrenia has been associated with a restrictive epigenome, and histone deacetylase (HDAC) inhibitors have...
6.
Lorca C, Fernandez-Rhodes M, Sanchez Milan J, Mulet M, Elortza F, Ramos-Miguel A, et al.
Biomedicines
. 2024 Jan;
12(1).
PMID: 38255234
Extracellular vesicles (EVs) are tiny membranous structures that mediate intercellular communication. The role(s) of these vesicles have been widely investigated in the context of neurological diseases; however, their potential implications...
7.
Yanez-Gomez F, Ramos-Miguel A, Garcia-Sevilla J, Manzanares J, Femenia T
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36768626
The crosstalk between the opioidergic system and mitogen-activated protein kinases (MAPKs) has a critical role in mediating stress-induced behaviors related to the pathophysiology of anxiety. The present study evaluated the...
8.
Casaletto K, Ramos-Miguel A, VandeBunte A, Memel M, Buchman A, Bennett D, et al.
Alzheimers Dement
. 2022 Jan;
18(11):2023-2035.
PMID: 34994517
Introduction: Physical activity (PA) is widely recommended for age-related brain health, yet its neurobiology is not well understood. Animal models indicate PA is synaptogenic. We examined the relationship between PA...
9.
Ramos-Miguel A, Jones A, Petyuk V, Barakauskas V, Barr A, Leurgans S, et al.
Acta Neuropathol
. 2021 Mar;
141(5):755-770.
PMID: 33646358
Age-related neuropathologies progressively impair cognitive abilities by damaging synaptic function. We aimed to identify key components within the presynaptic SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) machinery associated with cognitive...
10.
Ramos-Miguel A, Sanchez-Blazquez P, Garcia-Sevilla J
Pharmacol Rep
. 2021 Feb;
73(4):1122-1135.
PMID: 33641090
Background: Alpha-adrenergic (α-AR) and cannabinoid CB (CB-R) receptors exert their functions modulating multiple signaling pathways, including MEK-ERK (extracellular signal-regulated kinases) and FADD (Fas-associated protein with death domain) cascades. These molecules...