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Alexey A Larionov

Explore the profile of Alexey A Larionov including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 1128
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Recent Articles
1.
Rinschen M, Harder J, Carter-Timofte M, Zanon Rodriguez L, Mirabelli C, Demir F, et al.
Sci Signal . 2022 Nov; 15(762):eabo7940. PMID: 36445937
The lipid kinase VPS34 orchestrates autophagy, endocytosis, and metabolism and is implicated in cancer and metabolic disease. The proximal tubule in the kidney is a key metabolic organ that controls...
2.
Larionov A
Front Oncol . 2018 Apr; 8:89. PMID: 29670855
The median survival of patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) has more than doubled, since the discovery of HER2-targeted treatments: it rose from...
3.
Grahammer F, Ramakrishnan S, Rinschen M, Larionov A, Syed M, Khatib H, et al.
J Am Soc Nephrol . 2016 Jun; 28(1):230-241. PMID: 27297946
Renal proximal tubular cells constantly recycle nutrients to ensure minimal loss of vital substrates into the urine. Although most of the transport mechanisms have been discovered at the molecular level,...
4.
Turnbull A, Arthur L, Renshaw L, Larionov A, Kay C, Dunbier A, et al.
J Clin Oncol . 2015 Jun; 33(20):2270-8. PMID: 26033813
Purpose: Aromatase inhibitors (AIs) have an established role in the treatment of breast cancer. Response rates are only 50% to 70% in the neoadjuvant setting and lower in advanced disease....
5.
Toi M, Winer E, Benson J, Inamoto T, Forbes J, von Minckwitz G, et al.
Future Oncol . 2015 May; 11(9):1301-5. PMID: 25952778
Kyoto Breast Cancer Consensus Conference, Kyoto, Japan, 18-20 February 2014 The loco-regional management of breast cancer is increasingly complex with application of primary systemic therapies, oncoplastic techniques and genetic testing...
6.
Toi M, Winer E, Benson J, Inamoto T, Forbes J, von Minckwitz G, et al.
Future Oncol . 2015 May; 11(9):1297-300. PMID: 25952777
ABSTRACT  Kyoto Breast Cancer Consensus Conference, Kyoto, Japan, 18-20 February 2014 The loco-regional management of breast cancer is increasingly complex with application of primary systemic therapies, oncoplastic techniques and genetic...
7.
Arthur L, Turnbull A, Webber V, Larionov A, Renshaw L, Kay C, et al.
Cancer Res . 2014 Aug; 74(19):5371-6. PMID: 25100562
Invasive lobular carcinoma (ILC) accounts for approximately 10% to 15% of breast carcinomas, and although it responds poorly to neoadjuvant chemotherapy, it appears to respond well to endocrine therapy. Pre-...
8.
Sokolenko A, Bulanova D, Iyevleva A, Aleksakhina S, Preobrazhenskaya E, Ivantsov A, et al.
Int J Cancer . 2014 Jan; 134(10):2352-8. PMID: 24470238
In a search for new breast cancer (BC) predisposing genes, we performed a whole exome sequencing analysis using six patient samples of familial BC and identified a germline inactivating mutation...
9.
Sims A, Larionov A, Harrison D, Katz E
Methods Mol Biol . 2013 Jul; 1046:85-95. PMID: 23868583
The epithelial-to-mesenchymal transition (EMT) is a widely studied program of development of cells characterized by loss of cell adhesion, repression of E-cadherin expression, and increased cell mobility. Microarrays have become...
10.
Kuligina E, Sokolenko A, Mitiushkina N, Abysheva S, Preobrazhenskaya E, Gorodnova T, et al.
Fam Cancer . 2012 Oct; 12(1):129-32. PMID: 23104382
Virtually all known tumor predisposing genes have been identified via the analysis of familial cancer cases. Here we argue that this approach is likely to miss recessively acting cancer genes...