Alexei Kharitonenkov
Overview
Explore the profile of Alexei Kharitonenkov including associated specialties, affiliations and a list of published articles.
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73
Citations
7874
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Recent Articles
11.
Jager J, Wang F, Fang B, Lim H, Peed L, Steger D, et al.
J Biol Chem
. 2016 Mar;
291(20):10867-75.
PMID: 27002153
FGF21 is an atypical member of the FGF family that functions as a hormone to regulate carbohydrate and lipid metabolism. Here we demonstrate that the actions of FGF21 in mouse...
12.
Samms R, Cheng C, Kharitonenkov A, Gimeno R, Adams A
Endocrinology
. 2016 Feb;
157(4):1467-80.
PMID: 26901091
The endocrine hormone fibroblast growth factor 21 (FGF21) is induced in the adaptive response to nutrient deprivation, where it serves to regulate the integrated response to fasting via its primary...
13.
Kharitonenkov A, DiMarchi R
Trends Endocrinol Metab
. 2015 Oct;
26(11):608-617.
PMID: 26490383
The biology of fibroblast growth factor 21 (FGF21) has evolved through its first decade at a revolutionary pace with dramatic refinements in this relatively short span of time. This field...
14.
Samms R, Murphy M, Fowler M, Cooper S, Emmerson P, Coskun T, et al.
J Endocrinol
. 2015 Aug;
227(1):37-47.
PMID: 26294388
The aim of this study was to investigate the mechanisms by which fibroblast growth factor 21 (FGF21) affects hepatic integration of carbohydrate and fat metabolism in Siberian hamsters, a natural...
15.
Keipert S, Kutschke M, Lamp D, Brachthauser L, Neff F, Meyer C, et al.
Mol Metab
. 2015 Jul;
4(7):537-42.
PMID: 26137441
Objective: Circulating fibroblast growth factor 21 (FGF21) is an important auto- and endocrine player with beneficial metabolic effects on obesity and diabetes. In humans, thermogenic brown adipose tissue (BAT) was...
16.
Samms R, Smith D, Cheng C, Antonellis P, Perfield 2nd J, Kharitonenkov A, et al.
Cell Rep
. 2015 May;
11(7):991-9.
PMID: 25956583
A primary target of the pleiotropic metabolic hormone FGF21 is adipose tissue, where it initiates a gene expression program to enhance energy expenditure, an effect presumed to be centered on...
17.
Douris N, Stevanovic D, Fisher F, Cisu T, Chee M, Nguyen N, et al.
Endocrinology
. 2015 Apr;
156(7):2470-81.
PMID: 25924103
Fibroblast growth factor 21 (FGF21) has multiple metabolic actions, including the induction of browning in white adipose tissue. Although FGF21 stimulated browning results from a direct interaction between FGF21 and...
18.
Assini J, Mulvihill E, Burke A, Sutherland B, Telford D, Chhoker S, et al.
Endocrinology
. 2015 Mar;
156(6):2087-102.
PMID: 25774553
The molecular mechanisms and metabolic pathways whereby the citrus flavonoid, naringenin, reduces dyslipidemia and improves glucose tolerance were investigated in C57BL6/J wild-type mice and fibroblast growth factor 21 (FGF21) null...
19.
Emanuelli B, Vienberg S, Smyth G, Cheng C, Stanford K, Arumugam M, et al.
J Clin Invest
. 2015 Feb;
125(1):458.
PMID: 25654556
No abstract available.
20.
Zhang A, Sieglaff D, York J, Suh J, Ayers S, Winnier G, et al.
J Endocrinol
. 2014 Dec;
224(3):289-301.
PMID: 25501997
Thyroid hormone (TH) acts through specific receptors (TRs), which are conditional transcription factors, to induce fibroblast growth factor 21 (FGF21), a peptide hormone that is usually induced by fasting and...