Alexandra C McQuattie-Pimentel
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Explore the profile of Alexandra C McQuattie-Pimentel including associated specialties, affiliations and a list of published articles.
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14
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1743
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Recent Articles
1.
Stoeger T, Grant R, McQuattie-Pimentel A, Anekalla K, Liu S, Tejedor-Navarro H, et al.
Nat Aging
. 2023 Apr;
2(12):1191-1206.
PMID: 37118543
Aging is among the most important risk factors for morbidity and mortality. To contribute toward a molecular understanding of aging, we analyzed age-resolved transcriptomic data from multiple studies. Here, we...
2.
Watanabe S, Markov N, Lu Z, Aillon R, Soberanes S, Runyan C, et al.
Proc Natl Acad Sci U S A
. 2021 May;
118(20).
PMID: 33972447
Pulmonary fibrosis is a relentlessly progressive and often fatal disease with a paucity of available therapies. Genetic evidence implicates disordered epithelial repair, which is normally achieved by the differentiation of...
3.
McQuattie-Pimentel A, Ren Z, Joshi N, Watanabe S, Stoeger T, Chi M, et al.
J Clin Invest
. 2021 Feb;
131(4).
PMID: 33586677
Alveolar macrophages orchestrate the response to viral infections. Age-related changes in these cells may underlie the differential severity of pneumonia in older patients. We performed an integrated analysis of single-cell...
4.
Runyan C, Welch L, Lecuona E, Shigemura M, Amarelle L, Abdala-Valencia H, et al.
Aging Cell
. 2020 Jul;
19(9):e13180.
PMID: 32720752
Skeletal muscle dysfunction in survivors of pneumonia disproportionately affects older individuals in whom it causes substantial morbidity. We found that skeletal muscle recovery was impaired in old compared with young...
5.
Joshi N, Watanabe S, Verma R, Jablonski R, Chen C, Cheresh P, et al.
Eur Respir J
. 2019 Oct;
55(1).
PMID: 31601718
Ontologically distinct populations of macrophages differentially contribute to organ fibrosis through unknown mechanisms.We applied lineage tracing, single-cell RNA sequencing and single-molecule fluorescence hybridisation to a spatially restricted model of asbestos-induced...
6.
Soberanes S, Misharin A, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel A, Cho T, et al.
Cell Metab
. 2019 Feb;
29(2):503.
PMID: 30726761
No abstract available.
7.
Reyfman P, Walter J, Joshi N, Anekalla K, McQuattie-Pimentel A, Chiu S, et al.
Am J Respir Crit Care Med
. 2018 Dec;
199(12):1517-1536.
PMID: 30554520
The contributions of diverse cell populations in the human lung to pulmonary fibrosis pathogenesis are poorly understood. Single-cell RNA sequencing can reveal changes within individual cell populations during pulmonary fibrosis...
8.
Walter J, Ren Z, Yacoub T, Reyfman P, Shah R, Abdala-Valencia H, et al.
Am J Respir Crit Care Med
. 2018 Nov;
199(10):1225-1237.
PMID: 30398927
The identification of informative elements of the host response to infection may improve the diagnosis and management of bacterial pneumonia. To determine whether the absence of alveolar neutrophilia can exclude...
9.
Soberanes S, Misharin A, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel A, Cho T, et al.
Cell Metab
. 2018 Oct;
29(2):335-347.e5.
PMID: 30318339
Urban particulate matter air pollution induces the release of pro-inflammatory cytokines including interleukin-6 (IL-6) from alveolar macrophages, resulting in an increase in thrombosis. Here, we report that metformin provides protection...
10.
Ferguson K, McQuattie-Pimentel A, Malsin E, Sporn P
Am J Respir Cell Mol Biol
. 2018 Apr;
59(3):397-399.
PMID: 29641210
No abstract available.