Alexander V Emelyanov
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Explore the profile of Alexander V Emelyanov including associated specialties, affiliations and a list of published articles.
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25
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1663
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Recent Articles
11.
Emelyanov A, Rabbani J, Mehta M, Vershilova E, Keogh M, Fyodorov D
Genes Dev
. 2014 Sep;
28(18):2027-40.
PMID: 25228646
Nuclear DNA in the male gamete of sexually reproducing animals is organized as sperm chromatin compacted primarily by sperm-specific protamines. Fertilization leads to sperm chromatin remodeling, during which protamines are...
12.
Xu N, Emelyanov A, Fyodorov D, Skoultchi A
Epigenetics Chromatin
. 2014 Sep;
7:16.
PMID: 25177369
Background: Within the nucleus of eukaryotic cells, chromatin is organized into compact, silent regions called heterochromatin and more loosely packaged regions of euchromatin where transcription is more active. Although the...
13.
Lu X, Wontakal S, Kavi H, Kim B, Guzzardo P, Emelyanov A, et al.
Science
. 2013 Apr;
340(6128):78-81.
PMID: 23559249
Eukaryotic genomes harbor transposable elements and other repetitive sequences that must be silenced. Small RNA interference pathways play a major role in their repression. Here, we reveal another mechanism for...
14.
Emelyanov A, Vershilova E, Ignatyeva M, Pokrovsky D, Lu X, Konev A, et al.
Genes Dev
. 2012 Mar;
26(6):603-14.
PMID: 22426536
SNF2-like motor proteins, such as ISWI, cooperate with histone chaperones in the assembly and remodeling of chromatin. Here we describe a novel, evolutionarily conserved, ISWI-containing complex termed ToRC (Toutatis-containing chromatin...
15.
Chatterjee S, Ju Z, Hassan R, Volpi S, Emelyanov A, Birshtein B
J Biol Chem
. 2011 Jun;
286(33):29303-29312.
PMID: 21685395
The 3' regulatory region (3' RR) of the Igh locus works at long distances on variable region (V(H)) and switch region (I) region promoters to initiate germ line (non-coding) transcription...
16.
Emelyanov A, Konev A, Vershilova E, Fyodorov D
J Biol Chem
. 2010 Feb;
285(20):15027-15037.
PMID: 20154359
ATRX belongs to the family of SWI2/SNF2-like ATP-dependent nucleosome remodeling molecular motor proteins. Mutations of the human ATRX gene result in a severe genetic disorder termed X-linked alpha-thalassemia mental retardation...
17.
Lu X, Wontakal S, Emelyanov A, Morcillo P, Konev A, Fyodorov D, et al.
Genes Dev
. 2009 Feb;
23(4):452-65.
PMID: 19196654
We generated mutant alleles of Drosophila melanogaster in which expression of the linker histone H1 can be down-regulated over a wide range by RNAi. When the H1 protein level is...
18.
Giambra V, Volpi S, Emelyanov A, Pflugh D, Bothwell A, Norio P, et al.
Mol Cell Biol
. 2008 Jul;
28(19):6123-33.
PMID: 18644860
The 3' regulatory region (3' RR) of the murine immunoglobulin heavy chain (IgH) locus contains multiple DNase I-hypersensitive (hs) sites. Proximal sites hs3A, hs1.2, and hs3B are located in an...
19.
Konev A, Tribus M, Park S, Podhraski V, Lim C, Emelyanov A, et al.
Science
. 2007 Aug;
317(5841):1087-90.
PMID: 17717186
The organization of chromatin affects all aspects of nuclear DNA metabolism in eukaryotes. H3.3 is an evolutionarily conserved histone variant and a key substrate for replication-independent chromatin assembly. Elimination of...
20.
Nabatov A, Masharsky A, Verevochkin S, Emelyanov A, Lukashov V, Heimer R, et al.
AIDS Res Hum Retroviruses
. 2007 Mar;
23(2):183-92.
PMID: 17331025
The rate of processes accompanying the transition of the HIV-1 epidemic from nascent stage to concentrated one in the Former Soviet Union (FSU) during intravenous drug user (IDU)-associated HIV infection...