Dmitry V Fyodorov
Overview
Explore the profile of Dmitry V Fyodorov including associated specialties, affiliations and a list of published articles.
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27
Citations
2035
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Recent Articles
1.
ODwyer M, Azagury M, Furlong K, Alsheikh A, Hall-Ponsele E, Pinto H, et al.
Nature
. 2024 Dec;
638(8049):251-260.
PMID: 39695228
Cellular identity requires the concerted action of multiple transcription factors (TFs) bound together to enhancers of cell-type-specific genes. Despite TFs recognizing specific DNA motifs within accessible chromatin, this information is...
2.
Emelyanov A, Barcenilla-Merino D, Loppin B, Fyodorov D
J Biol Chem
. 2023 Sep;
299(10):105212.
PMID: 37660905
DNA in sperm is packed with small, charged proteins termed SNBPs (sperm nuclear basic proteins), including mammalian and Drosophila protamines. During spermiogenesis, somatic-type chromatin is taken apart and replaced with...
3.
Andreyeva E, Emelyanov A, Nevil M, Sun L, Vershilova E, Hill C, et al.
Elife
. 2022 Dec;
11.
PMID: 36458689
Asynchronous replication of chromosome domains during S phase is essential for eukaryotic genome function, but the mechanisms establishing which domains replicate early versus late in different cell types remain incompletely...
4.
Schoberleitner I, Bauer I, Huang A, Andreyeva E, Sebald J, Pascher K, et al.
Cell Rep
. 2021 Oct;
37(1):109769.
PMID: 34610319
The ATP-dependent chromatin remodeling factor CHD1 is essential for the assembly of variant histone H3.3 into paternal chromatin during sperm chromatin remodeling in fertilized eggs. It remains unclear, however, if...
5.
Fyodorov D, Zhou B, Skoultchi A, Bai Y
Nat Rev Mol Cell Biol
. 2017 Oct;
19(3):192-206.
PMID: 29018282
Together with core histones, which make up the nucleosome, the linker histone (H1) is one of the five main histone protein families present in chromatin in eukaryotic cells. H1 binds...
6.
Strom A, Emelyanov A, Mir M, Fyodorov D, Darzacq X, Karpen G
Nature
. 2017 Jun;
547(7662):241-245.
PMID: 28636597
Constitutive heterochromatin is an important component of eukaryotic genomes that has essential roles in nuclear architecture, DNA repair and genome stability, and silencing of transposon and gene expression. Heterochromatin is...
7.
Andreyeva E, Bernardo T, Kolesnikova T, Lu X, Yarinich L, Bartholdy B, et al.
Genes Dev
. 2017 Apr;
31(6):603-616.
PMID: 28404631
Eukaryotic DNA replicates asynchronously, with discrete genomic loci replicating during different stages of S phase. larval tissues undergo endoreplication without cell division, and the latest replicating regions occasionally fail to...
8.
Emelyanov A, Fyodorov D
Genes Dev
. 2016 Dec;
30(24):2651-2656.
PMID: 28031247
Cysteine oxidation in protamines leads to their oligomerization and contributes to sperm chromatin compaction. Here we identify the Drosophila thioredoxin Deadhead (DHD) as the factor responsible for the reduction of...
9.
Xu N, Lu X, Kavi H, Emelyanov A, Bernardo T, Vershilova E, et al.
Sci Rep
. 2016 Oct;
6:34354.
PMID: 27687115
Metazoan linker histones are essential for development and play crucial roles in organization of chromatin, modification of epigenetic states and regulation of genetic activity. Vertebrates express multiple linker histone H1...
10.
Kavi H, Emelyanov A, Fyodorov D, Skoultchi A
J Biol Chem
. 2016 May;
291(29):15143-55.
PMID: 27226620
Linker histone H1 is among the most abundant components of chromatin. H1 has profound effects on chromosome architecture. H1 also helps to tether DNA- and histone-modifying enzymes to chromatin. Metazoan...