Alexander Sedykh
Overview
Explore the profile of Alexander Sedykh including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
1088
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Recent Articles
1.
Ford L, Lin H, Zhou Y, Wright F, Gombar V, Sedykh A, et al.
Hum Genomics
. 2024 Sep;
18(1):92.
PMID: 39218963
Per- and poly-fluoroalkyl substances (PFAS) are emerging contaminants of concern because of their wide use, persistence, and potential to be hazardous to both humans and the environment. Several PFAS have...
2.
Ford L, Lin H, Tsai H, Zhou Y, Wright F, Sedykh A, et al.
Toxicology
. 2024 Feb;
503:153763.
PMID: 38423244
Per- and poly-fluoroalkyl substances (PFAS) are extensively used in commerce leading to their prevalence in the environment. Due to their chemical stability, PFAS are considered to be persistent and bioaccumulative;...
3.
Sedykh A, Choksi N, Allen D, Casey W, Shah R, Kleinstreuer N
Chem Res Toxicol
. 2022 May;
35(6):992-1000.
PMID: 35549170
Computational modeling grounded in reliable experimental data can help design effective non-animal approaches to predict the eye irritation and corrosion potential of chemicals. The National Toxicology Program (NTP) Interagency Center...
4.
Sedykh A
Methods Mol Biol
. 2022 Mar;
2474:147-154.
PMID: 35294763
The nature of high-throughput screening (HTS) puts certain limits on optimal test conditions for each particular sample; therefore, on top of usual data normalization, additional parsing is often needed to...
5.
Hsieh J, Sedykh A, Mutlu E, Germolec D, Auerbach S, Rider C
Chem Res Toxicol
. 2020 Oct;
34(2):268-285.
PMID: 33063992
Polycyclic aromatic compounds (PACs) are compounds with a minimum of two six-atom aromatic fused rings. PACs arise from incomplete combustion or thermal decomposition of organic matter and are ubiquitous in...
6.
Yan X, Sedykh A, Wang W, Yan B, Zhu H
Nat Commun
. 2020 May;
11(1):2519.
PMID: 32433469
Modern nanotechnology research has generated numerous experimental data for various nanomaterials. However, the few nanomaterial databases available are not suitable for modeling studies due to the way they are curated....
7.
Sorg J, Schneider T, Wohlfarth L, Schafer T, Sedykh A, Muller-Buschbaum K
Dalton Trans
. 2020 Apr;
49(15):4904-4913.
PMID: 32232237
Fifteen new sublimable Sb- and Bi-based chlorido, bromido and iodido coordination polymers (CPs) with linear bispyridyl ligands are presented in this work and compared in terms of their crystal structures...
8.
Yoo J, Kruhlak N, Landry C, Cross K, Sedykh A, Stavitskaya L
Regul Toxicol Pharmacol
. 2020 Feb;
113:104620.
PMID: 32092371
All drugs entering clinical trials are expected to undergo a series of in vitro and in vivo genotoxicity tests as outlined in the International Council on Harmonization (ICH) S2 (R1)...
9.
Liu G, Yan X, Sedykh A, Pan X, Zhao X, Yan B, et al.
Ecotoxicol Environ Saf
. 2020 Jan;
191:110216.
PMID: 31972454
Health risks induced by PM2.5 have become one of the major concerns among living populations, especially in regions facing serious pollution such as China and India. Furthermore, the composition of...
10.
Hsieh J, Smith-Roe S, Huang R, Sedykh A, Shockley K, Auerbach S, et al.
Chem Res Toxicol
. 2019 Jun;
32(7):1384-1401.
PMID: 31243984
Genotoxicity is a critical component of a comprehensive toxicological profile. The Tox21 Program used five quantitative high-throughput screening (qHTS) assays measuring some aspect of DNA damage/repair to provide information on...