Alexander Scherl
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Explore the profile of Alexander Scherl including associated specialties, affiliations and a list of published articles.
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49
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1083
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Recent Articles
21.
Ahrne E, Ohta Y, Nikitin F, Scherl A, Lisacek F, Muller M
Proteomics
. 2011 Sep;
11(20):4085-95.
PMID: 21898822
The relevance of libraries of annotated MS/MS spectra is growing with the amount of proteomic data generated in high-throughput experiments. These reference libraries provide a fast and accurate way to...
22.
Kistler A, Siwy J, Breunig F, Jeevaratnam P, Scherl A, Mullen W, et al.
PLoS One
. 2011 Jun;
6(6):e20534.
PMID: 21698285
Female patients affected by Fabry disease, an X-linked lysosomal storage disorder, exhibit a wide spectrum of symptoms, which renders diagnosis, and treatment decisions challenging. No diagnostic test, other than sequencing...
23.
Priego-Capote F, Ramirez-Boo M, Hoogland C, Scherl A, Mueller M, Lisacek F, et al.
Anal Chem
. 2011 Jun;
83(14):5673-80.
PMID: 21630644
Despite continuous advances in hyperglycemia treatments, a precise control through monitoring of glucose and glycated hemoglobin remains in most diabetic patients as the diagnosis/prognosis tool. An alternative perspective could be...
24.
Fischer A, Yang S, Bayer A, Vaezzadeh A, Herzig S, Stenz L, et al.
J Antimicrob Chemother
. 2011 May;
66(8):1696-711.
PMID: 21622973
Objectives: The development of daptomycin resistance in Staphylococcus aureus is associated with clinical treatment failures. The mechanism(s) of such resistance have not been clearly defined. Methods: We studied an isogenic...
25.
Dayon L, Turck N, Scherl A, Hochstrasser D, Burkhard P, Sanchez J
Chimia (Aarau)
. 2010 Dec;
64(3):132-5.
PMID: 21140904
Quantification is a major task in proteomics. Among the different analytical strategies to enable peptide and protein quantification, tagging with isotopic labels has emerged as a practical, versatile, and efficient...
26.
Nguyen-Lefebvre A, Gonin-Giraud S, Scherl A, Arboit P, Granger L, Sanchez J, et al.
J Proteomics
. 2010 Nov;
74(2):167-85.
PMID: 21055487
To identify the exact spot position of human, rat and chicken ribosomal proteins (RP) separated by two-dimensional polyacrylamide gel electrophoresis (2-DE), a 2-DE system was designed to separate RP with...
27.
Tiberti N, Hainard A, Lejon V, Robin X, Ngoyi D, Turck N, et al.
Mol Cell Proteomics
. 2010 Aug;
9(12):2783-95.
PMID: 20724469
Human African trypanosomiasis, or sleeping sickness, is a parasitic disease endemic in sub-Saharan Africa, transmitted to humans through the bite of a tsetse fly. The first or hemolymphatic stage of...
28.
Dayon L, Turck N, Kienle S, Schulz-Knappe P, Hochstrasser D, Scherl A, et al.
Anal Chem
. 2010 Jan;
82(3):848-58.
PMID: 20058875
In the past few years, mass spectrometry (MS) has emerged as an efficient tool for the multiplexed peptide and protein concentration determination by isotope dilution. Despite the growing use of...
29.
Priego-Capote F, Scherl A, Muller M, Waridel P, Lisacek F, Sanchez J
Mol Cell Proteomics
. 2009 Dec;
9(3):579-92.
PMID: 19955080
Non-enzymatic glycation of proteins is a post-translational modification produced by a reaction between reducing sugars and amino groups located in lysine and arginine residues or in the N-terminal position. This...
30.
Dayon L, Pasquarello C, Hoogland C, Sanchez J, Scherl A
J Proteomics
. 2009 Nov;
73(4):769-77.
PMID: 19903544
Isobaric tagging, via TMT or iTRAQ, is widely used in quantitative proteomics. To date, tandem mass spectrometric analysis of isobarically-labeled peptides with hybrid ion trap-orbitrap (LTQ-OT) instruments has been mainly...