Alexander Scherl
Overview
Explore the profile of Alexander Scherl including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
1083
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Recent Articles
1.
Piletta-Zanin A, Scherl A, Benhamou A, Braendle G, Caubet J, Graham F, et al.
Allergy
. 2024 Nov;
80(1):238-247.
PMID: 39606880
Introduction: Patients with food allergies need personalized information on their risk of reaction in "real-life" situations. This multicentric study aimed to investigate the link during accidental reactions between the nature...
2.
Lassout O, Hartmer R, Jabs W, Clerici L, Tsybin Y, Samii K, et al.
Clin Proteomics
. 2020 Jan;
16:41.
PMID: 31889938
Background: Biological diagnosis of hemoglobin disorders is a complex process relying on the combination of several analytical techniques to identify Hb variants in a particular sample. Currently, hematology laboratories usually...
3.
Coelho Graca D, Hartmer R, Jabs W, Scherl A, Clerici L, Samii K, et al.
Methods Mol Biol
. 2019 Mar;
1959:173-183.
PMID: 30852823
Characterization of protein structure modifications is an important field in mass spectrometry (MS)-based proteomics. Here, we describe a process to quickly and reliably identify a mass change in a targeted...
4.
Acosta-Martin A, Antinori P, Uppugunduri C, Daali Y, Ansari M, Scherl A, et al.
Rapid Commun Mass Spectrom
. 2016 Sep;
30(23):2517-2528.
PMID: 27599297
Rationale: Busulfan is a bifunctional alkyl sulfonate antineoplastic drug. This alkylating agent was described as forming covalent adducts on proteins. However, only limited data are available regarding the interaction of...
5.
Campos A, Diaz R, Martinez-Bartolome S, Sierra J, Gallardo O, Sabido E, et al.
J Proteomics
. 2015 May;
127(Pt B):264-74.
PMID: 25982386
Proteomic technologies based on mass spectrometry (MS) have greatly evolved in the past years, and nowadays it is possible to routinely identify thousands of peptides from complex biological samples in...
6.
Coelho Graca D, Hartmer R, Jabs W, Beris P, Clerici L, Stoermer C, et al.
Anal Bioanal Chem
. 2015 Mar;
407(10):2837-45.
PMID: 25753013
Hemoglobin disorder diagnosis is a complex procedure combining several analytical steps. Due to the lack of specificity of the currently used protein analysis methods, the identification of uncommon hemoglobin variants...
7.
Scherl A
Methods
. 2015 Mar;
81:3-14.
PMID: 25752846
Quantitative protein analysis is routinely performed in clinical chemistry laboratories for diagnosis, therapeutic monitoring, and prognosis. Today, protein assays are mostly performed either with non-specific detection methods or immunoassays. Mass...
8.
von Tobel J, Antinori P, Zurich M, Rosset R, Aschner M, Gluck F, et al.
Neurotoxicology
. 2014 May;
44:61-70.
PMID: 24792326
Neurotoxic effects of the environmentally abundant mycotoxin Ochratoxin A (OTA) were studied in histotypic 3D rat brain cell cultures, comprising all brain cell types. Cultures were exposed to nanomolar OTA...
9.
von Tobel J, Zoia D, Althaus J, Antinori P, Mermoud J, Pak H, et al.
Toxicol Lett
. 2014 Feb;
230(2):188-97.
PMID: 24521700
Xenobiotic exposure is a risk factor in the etiology of neurodegenerative disease. It was recently hypothesized that restricted exposure during brain development could predispose for a neurodegenerative disease later in...
10.
Steiner C, Ducret A, Tille J, Thomas M, McKee T, Rubbia-Brandt L, et al.
Proteomics
. 2013 Dec;
14(4-5):441-51.
PMID: 24339433
Proteomic analysis of tissues has advanced in recent years as instruments and methodologies have evolved. The ability to retrieve peptides from formalin-fixed paraffin-embedded tissues followed by shotgun or targeted proteomic...