Alexander O Subtelny
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Explore the profile of Alexander O Subtelny including associated specialties, affiliations and a list of published articles.
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16
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1125
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Recent Articles
1.
Mei S, Alchahin A, Tsea I, Kfoury Y, Hirz T, Jeffries N, et al.
Genome Med
. 2024 Jan;
16(1):1.
PMID: 38281962
Background: Despite therapeutic advances, once a cancer has metastasized to the bone, it represents a highly morbid and lethal disease. One third of patients with advanced clear cell renal cell...
2.
Hirz T, Mei S, Sarkar H, Kfoury Y, Wu S, Verhoeven B, et al.
Nat Commun
. 2023 Feb;
14(1):663.
PMID: 36750562
The treatment of low-risk primary prostate cancer entails active surveillance only, while high-risk disease requires multimodal treatment including surgery, radiation therapy, and hormonal therapy. Recurrence and development of metastatic disease...
3.
Alchahin A, Mei S, Tsea I, Hirz T, Kfoury Y, Dahl D, et al.
Nat Commun
. 2022 Sep;
13(1):5747.
PMID: 36180422
Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer in adults. When ccRCC is localized to the kidney, surgical resection or ablation of the tumor...
4.
Wu S, Lin S, Wirth G, Lu M, Lu J, Subtelny A, et al.
Am J Clin Oncol
. 2020 Oct;
43(12):872-879.
PMID: 33002923
Objective: The objective of this study was to evaluate the impact of the anterior/posterior status of positive surgical margin (PSM) on long-term outcomes after radical prostatectomy for prostate cancer. Patients...
5.
Eisen T, Eichhorn S, Subtelny A, Lin K, McGeary S, Gupta S, et al.
Mol Cell
. 2020 Jan;
77(4):786-799.e10.
PMID: 31902669
For all but a few mRNAs, the dynamics of metabolism are unknown. Here, we developed an experimental and analytical framework for examining these dynamics for mRNAs from thousands of genes....
6.
Eisen T, Eichhorn S, Subtelny A, Bartel D
Mol Cell
. 2020 Jan;
77(4):775-785.e8.
PMID: 31902668
MicroRNAs (miRNAs) specify the recruitment of deadenylases to mRNA targets. Despite this recruitment, we find that miRNAs have almost no effect on steady-state poly(A)-tail lengths of their targets in mouse...
7.
Wu S, Lin S, Lu M, Subtelny A, Wang Z, Dahl D, et al.
Int Urol Nephrol
. 2019 Jun;
51(9):1527-1535.
PMID: 31183659
Objective: To investigate the oncological impact of incidental prostate cancer (iPCa) found during radical cystoprostatectomy (RCP) on overall survival (OS) prognosis of urothelial carcinoma of the bladder (BCa). Patients And...
8.
Wu S, Lin S, Wirth G, Lu M, Lu J, Subtelny A, et al.
Clin Genitourin Cancer
. 2018 Oct;
17(1):e44-e52.
PMID: 30287224
Objective: To assess the impact of focality and location of positive surgical margins (PSM) on long-term outcomes after radical prostatectomy (RP) for prostate cancer (PCa), including biochemical recurrence (BCR), metastasis...
9.
Agarwal V, Subtelny A, Thiru P, Ulitsky I, Bartel D
Genome Biol
. 2018 Oct;
19(1):152.
PMID: 30286781
Background: MicroRNAs (miRNAs) are short regulatory RNAs that derive from hairpin precursors. Important for understanding the functional roles of miRNAs is the ability to predict the messenger RNA (mRNA) targets...
10.
Rissland O, Subtelny A, Wang M, Lugowski A, Nicholson B, Laver J, et al.
Genome Biol
. 2017 Nov;
18(1):211.
PMID: 29089021
Background: All mRNAs are bound in vivo by proteins to form mRNA-protein complexes (mRNPs), but changes in the composition of mRNPs during posttranscriptional regulation remain largely unexplored. Here, we have...