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Alexander Lemenze

Explore the profile of Alexander Lemenze including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 171
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Recent Articles
1.
Sanchez G, Hirsch E, VanValkenburg A, Mayer D, Gbedande K, Francis R, et al.
Cell Rep . 2024 Nov; 43(11):114978. PMID: 39527476
Autoimmune diseases such as lupus are characterized by polyclonal B cell activation, leading to the production of autoantibodies. The mechanism leading to B cell dysregulation is unclear; however, the defect...
2.
Gungor Aydin A, Lemenze A, Bieszczad K
Sci Rep . 2024 Oct; 14(1):25314. PMID: 39455606
The mammalian cerebral cortex is composed of a rich diversity of cell types. Sensory cortical cells are organized into networks that rely on their functional diversity to ultimately carry out...
3.
Deng D, Begum H, Liu T, Zhang J, Zhang Q, Chu T, et al.
J Exp Med . 2024 Oct; 221(11). PMID: 39432061
Resistance to KRAS therapy in pancreatic ductal adenocarcinoma (PDAC) involves cellular plasticity, particularly the epithelial-to-mesenchymal transition (EMT), which poses challenges for effective targeting. Chronic pancreatitis, a known risk factor for...
4.
Peignier A, Kim J, Lemenze A, Parker D
PLoS Pathog . 2024 Oct; 20(10):e1012648. PMID: 39418302
Staphylococcus aureus is a versatile bacterium responsible for conditions ranging from mild skin and soft-tissue infections to serious disorders such as pneumonia and sepsis. Monocytes play a role in protection...
5.
Joseph J, Premeaux T, Tandon R, Murphy E, Bruhn R, Nicot C, et al.
Viruses . 2024 Sep; 16(9). PMID: 39339919
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive demyelinating disease of the spinal cord due to chronic inflammation. Hallmarks of disease pathology include dysfunctional anti-viral responses and the infiltration of...
6.
Wang K, Espinosa V, Wang Y, Lemenze A, Kumamoto Y, Xue C, et al.
mBio . 2024 Sep; 15(10):e0194424. PMID: 39324785
Fungal pathogens are underappreciated causes of significant morbidity and mortality worldwide. In previous studies, we determined that a heat-killed, fbp1-deficient strain (HK-fbp1) is a potent vaccine candidate. We determined that...
7.
Eaton W, Hamilton D, Chen W, Lemenze A, Soteropoulos P
AIMS Microbiol . 2024 Sep; 10(3):572-595. PMID: 39219756
Leguminous tree root nodule nitrogen-fixing bacteria are critical for recuperation of soil C and N cycle processes after disturbance in tropical forests, while other nodule-associated bacteria (NAB) may enhance nodule...
8.
Lothstein K, Chen F, Mishra P, Smyth D, Wu W, Lemenze A, et al.
Life Sci Alliance . 2024 Aug; 7(11). PMID: 39179288
Skin wound healing due to full thickness wounds typically results in fibrosis and scarring, where parenchyma tissue is replaced with connective tissue. A major advance in wound healing research would...
9.
Hu W, Kaluzova M, Dawson A, Sotelo V, Papas J, Lemenze A, et al.
Cell Rep Med . 2024 May; 5(5):101561. PMID: 38744274
Natural history and mechanisms for persistent cognitive symptoms ("brain fog") following acute and often mild COVID-19 are unknown. In a large prospective cohort of people who underwent testing a median...
10.
Gungor Aydin A, Lemenze A, Bieszczad K
bioRxiv . 2024 Apr; PMID: 38659766
The mammalian cerebral cortex is composed of a rich diversity of cell types. Cortical cells are organized into networks that rely on their functional diversity to ultimately carry out a...