Alexander G Fletcher
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Explore the profile of Alexander G Fletcher including associated specialties, affiliations and a list of published articles.
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Articles
62
Citations
1611
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Recent Articles
11.
Nestor-Bergmann A, Blanchard G, Hervieux N, Fletcher A, Etienne J, Sanson B
PLoS Comput Biol
. 2022 Jan;
18(1):e1009812.
PMID: 35089922
Cell intercalation is a key cell behaviour of morphogenesis and wound healing, where local cell neighbour exchanges can cause dramatic tissue deformations such as body axis extension. Substantial experimental work...
12.
Fletcher A, Osborne J
WIREs Mech Dis
. 2022 Jan;
14(1):e1527.
PMID: 35023326
The growth and dynamics of multicellular tissues involve tightly regulated and coordinated morphogenetic cell behaviors, such as shape changes, movement, and division, which are governed by subcellular machinery and involve...
13.
Niehus R, Oliveira N, Li A, Fletcher A, Foster K
Elife
. 2021 Sep;
10.
PMID: 34488940
Bacteria inhibit and kill one another with a diverse array of compounds, including bacteriocins and antibiotics. These attacks are highly regulated, but we lack a clear understanding of the evolutionary...
14.
Gonay L, Spourquet C, Baudoin M, Lepers L, Lemoine P, Fletcher A, et al.
Front Endocrinol (Lausanne)
. 2021 Jun;
12:655862.
PMID: 34163435
Organogenesis is the phase of embryonic development leading to the formation of fully functional organs. In the case of the thyroid, organogenesis starts from the endoderm and generates a multitude...
15.
Groves I, Placzek M, Fletcher A
Philos Trans R Soc Lond B Biol Sci
. 2020 Aug;
375(1809):20190660.
PMID: 32829689
Sonic Hedgehog (Shh) Is a critical protein in vertebrate development, orchestrating patterning and growth in many developing systems. First described as a classic morphogen that patterns tissues through a spatial...
16.
Campbell K, Noel E, Fletcher A, Bulgakova N
Philos Trans R Soc Lond B Biol Sci
. 2020 Aug;
375(1809):20190549.
PMID: 32829677
No abstract available.
17.
Gorochowski T, Hauert S, Kreft J, Marucci L, Stillman N, Tang T, et al.
Front Bioeng Biotechnol
. 2020 Jul;
8:705.
PMID: 32671054
Many complex behaviors in biological systems emerge from large populations of interacting molecules or cells, generating functions that go beyond the capabilities of the individual parts. Such collective phenomena are...
18.
Ruske L, Kursawe J, Tsakiridis A, Wilson V, Fletcher A, Blythe R, et al.
Phys Biol
. 2020 Jun;
17(6):065009.
PMID: 32585646
The deluge of single-cell data obtained by sequencing, imaging and epigenetic markers has led to an increasingly detailed description of cell state. However, it remains challenging to identify how cells...
19.
Grimes D, Fletcher A
Bull Math Biol
. 2020 Jan;
82(2):20.
PMID: 31970500
Cancer is a complex phenomenon, and the sheer variation in behaviour across different types renders it difficult to ascertain underlying biological mechanisms. Experimental approaches frequently yield conflicting results for myriad...
20.
Finegan T, Hervieux N, Nestor-Bergmann A, Fletcher A, Blanchard G, Sanson B
PLoS Biol
. 2019 Dec;
17(12):e3000522.
PMID: 31805038
In epithelia, tricellular vertices are emerging as important sites for the regulation of epithelial integrity and function. Compared to bicellular contacts, however, much less is known. In particular, resident proteins...