Alexander Amatuni
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Explore the profile of Alexander Amatuni including associated specialties, affiliations and a list of published articles.
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5
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54
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Recent Articles
1.
Morstein J, Amatuni A, Shuster A, Kuttenlochner W, Ko T, Abegg D, et al.
Angew Chem Int Ed Engl
. 2023 Dec;
63(8):e202314791.
PMID: 38109686
Photolipids have emerged as attractive tools for the optical control of lipid functions. They often contain an azobenzene photoswitch that imparts a cis double-bond upon irradiation. Herein, we present the...
2.
Amatuni A, Shuster A, Abegg D, Adibekian A, Renata H
ACS Cent Sci
. 2023 Feb;
9(2):239-251.
PMID: 36844499
The cepafungins are a class of highly potent and selective eukaryotic proteasome inhibitor natural products with potential to treat refractory multiple myeloma and other cancers. The structure-activity relationship of the...
3.
Amatuni A, Shuster A, Adibekian A, Renata H
Cell Chem Biol
. 2020 Aug;
27(10):1318-1326.e18.
PMID: 32763140
The natural product cepafungin I was recently reported to be one of the most potent covalent inhibitors of the 20S proteasome core particle through a series of in vitro activity...
4.
Li J, Amatuni A, Renata H
Curr Opin Chem Biol
. 2020 Feb;
55:111-118.
PMID: 32086167
The field of organic chemistry has recently witnessed a rapid rise in the use of chemoenzymatic strategies for the synthesis of complex molecules. Under this paradigm, biocatalytic methods and contemporary...
5.
Amatuni A, Renata H
Org Biomol Chem
. 2018 Oct;
17(7):1736-1739.
PMID: 30320324
We present the functional characterization of GlbB, a lysine 4-hydroxylase from the glidobactin biosynthetic gene cluster. Despite its narrow substrate specificity, GlbB is able to catalyze the hydroxylation of l-lysine...