Alex Yick-Lun So
Overview
Explore the profile of Alex Yick-Lun So including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
982
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Li G, So A, Sookram R, Wong S, Wang J, Ouyang Y, et al.
Blood
. 2018 Mar;
131(17):1920-1930.
PMID: 29555645
Deregulation of several microRNAs (miRs) can influence critical developmental checkpoints during hematopoiesis as well as cell functions, eventually leading to the development of autoimmune disease or cancer. We found that...
2.
So A, Sookram R, Chaudhuri A, Minisandram A, Cheng D, Xie C, et al.
Blood
. 2014 Jul;
124(9):1502-12.
PMID: 25006123
The oncomir microRNA-125b (miR-125b) is upregulated in a variety of human neoplastic blood disorders and constitutive upregulation of miR-125b in mice can promote myeloid and B-cell leukemia. We found that...
3.
Haldar M, Kohyama M, So A, Kc W, Wu X, Briseno C, et al.
Cell
. 2014 Mar;
156(6):1223-1234.
PMID: 24630724
Splenic red pulp macrophages (RPM) degrade senescent erythrocytes and recycle heme-associated iron. The transcription factor SPI-C is selectively expressed by RPM and is required for their development, but the physiologic...
4.
So A, Zhao J, Baltimore D
Immunol Rev
. 2013 Apr;
253(1):129-45.
PMID: 23550643
Yin and Yang are two complementary forces that together describe the nature of real-world elements. Yin is the dark side; Yang is the light side. We describe microRNAs having both...
5.
So A, Garcia-Flores Y, Minisandram A, Martin A, Taganov K, Boldin M, et al.
Blood
. 2012 Jul;
120(12):2428-37.
PMID: 22791292
APCs are essential for innate and adaptive immunity as well as self-immune tolerance. Here, we show that the Cap'n'collar member Bach1 regulates the generation of APCs, specifically macrophages and dendritic...
6.
Chaudhuri A, So A, Mehta A, Minisandram A, Sinha N, Jonsson V, et al.
Proc Natl Acad Sci U S A
. 2012 Feb;
109(11):4233-8.
PMID: 22366319
MicroRNA-125b (miR-125b) is up-regulated in patients with leukemia. Overexpression of miR-125b alone in mice causes a very aggressive, transplantable myeloid leukemia. Before leukemia, these mice do not display elevation of...
7.
Chaudhuri A, So A, Sinha N, Gibson W, Taganov K, OConnell R, et al.
J Immunol
. 2011 Oct;
187(10):5062-8.
PMID: 22003200
MicroRNA (miR)-125b expression is modulated in macrophages in response to stimulatory cues. In this study, we report a functional role of miR-125b in macrophages. We found that miR-125b is enriched...
8.
Ou C, LaBonte M, Manegold P, So A, Ianculescu I, Gerke D, et al.
Mol Cancer Res
. 2011 Apr;
9(5):660-70.
PMID: 21478268
Aberrant activation of Wnt/β-catenin signaling, resulting in the expression of Wnt-regulated oncogenes, is recognized as a critical factor in the etiology of colorectal cancer. Occupancy of β-catenin at promoters of...
9.
Koliwad S, Kuo T, Shipp L, Gray N, Backhed F, So A, et al.
J Biol Chem
. 2009 Jul;
284(38):25593-601.
PMID: 19628874
Glucocorticoids are important regulators of lipid homeostasis, and chronically elevated glucocorticoid levels induce hypertriglyceridemia, hepatic steatosis, and visceral obesity. The occupied glucocorticoid receptor (GR) is a transcription factor. However, those...
10.
So A, de la Fuente E, Walter P, Shuman M, Bernales S
Cancer Metastasis Rev
. 2009 Jan;
28(1-2):219-23.
PMID: 19172382
Accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces the unfolded protein response (UPR). The UPR promotes cell survival by adjusting ER protein folding capacity but if homeostasis cannot...