Alex Dobin
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Explore the profile of Alex Dobin including associated specialties, affiliations and a list of published articles.
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11
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5359
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Recent Articles
1.
Hitz B, Lee J, Jolanki O, Kagda M, Graham K, Sud P, et al.
Res Sq
. 2023 Jul;
PMID: 37503119
The Encyclopedia of DNA elements (ENCODE) project is a collaborative effort to create a comprehensive catalog of functional elements in the human genome. The current database comprises more than 19000...
2.
Hitz B, Jin-Wook L, Jolanki O, Kagda M, Graham K, Sud P, et al.
bioRxiv
. 2023 Apr;
PMID: 37066421
The Encyclopedia of DNA elements (ENCODE) project is a collaborative effort to create a comprehensive catalog of functional elements in the human genome. The current database comprises more than 19000...
3.
Rahmanian S, Murad R, Breschi A, Zeng W, Mackiewicz M, Williams B, et al.
Genome Res
. 2019 Oct;
29(11):1900-1909.
PMID: 31645363
MicroRNAs (miRNAs) play a critical role as posttranscriptional regulators of gene expression. The ENCODE Project profiled the expression of miRNAs in an extensive set of organs during a time-course of...
4.
Breschi A, Djebali S, Gillis J, Pervouchine D, Dobin A, Davis C, et al.
Genome Biol
. 2016 Jul;
17(1):151.
PMID: 27391956
Background: A comparison of transcriptional profiles derived from different tissues in a given species or among different species assumes that commonalities reflect evolutionarily conserved programs and that differences reflect species...
5.
Pervouchine D, Djebali S, Breschi A, Davis C, Prieto Barja P, Dobin A, et al.
Nat Commun
. 2015 Jan;
6:5903.
PMID: 25582907
Mice have been a long-standing model for human biology and disease. Here we characterize, by RNA sequencing, the transcriptional profiles of a large and heterogeneous collection of mouse tissues, augmenting...
6.
Yue F, Cheng Y, Breschi A, Vierstra J, Wu W, Ryba T, et al.
Nature
. 2014 Nov;
515(7527):355-64.
PMID: 25409824
The laboratory mouse shares the majority of its protein-coding genes with humans, making it the premier model organism in biomedical research, yet the two mammals differ in significant ways. To...
7.
Gerstein M, Rozowsky J, Yan K, Wang D, Cheng C, Brown J, et al.
Nature
. 2014 Aug;
512(7515):445-8.
PMID: 25164755
The transcriptome is the readout of the genome. Identifying common features in it across distant species can reveal fundamental principles. To this end, the ENCODE and modENCODE consortia have generated...
8.
Djebali S, Davis C, Merkel A, Dobin A, Lassmann T, Mortazavi A, et al.
Nature
. 2012 Sep;
489(7414):101-8.
PMID: 22955620
Eukaryotic cells make many types of primary and processed RNAs that are found either in specific subcellular compartments or throughout the cells. A complete catalogue of these RNAs is not...
9.
Stamatoyannopoulos J, Snyder M, Hardison R, Ren B, Gingeras T, Gilbert D, et al.
Genome Biol
. 2012 Aug;
13(8):418.
PMID: 22889292
To complement the human Encyclopedia of DNA Elements (ENCODE) project and to enable a broad range of mouse genomics efforts, the Mouse ENCODE Consortium is applying the same experimental pipelines...
10.
Djebali S, Lagarde J, Kapranov P, Lacroix V, Borel C, Mudge J, et al.
PLoS One
. 2012 Jan;
7(1):e28213.
PMID: 22238572
The classic organization of a gene structure has followed the Jacob and Monod bacterial gene model proposed more than 50 years ago. Since then, empirical determinations of the complexity of...