Alex C Tuck
Overview
Explore the profile of Alex C Tuck including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
9
Citations
454
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bieler J, Pozzorini C, Garcia J, Tuck A, Macheret M, Willig A, et al.
JCO Clin Cancer Inform
. 2021 Nov;
5:1085-1095.
PMID: 34731027
Purpose: The ability of next-generation sequencing (NGS) assays to interrogate thousands of genomic loci has revolutionized genetic testing. However, translation to the clinic is impeded by false-negative results that pose...
2.
Tuck A, Buhler M
Methods Mol Biol
. 2020 Jul;
2167:287-301.
PMID: 32712926
Some long non-coding RNA (lncRNA) genes encode a functional RNA product, whereas others act as DNA elements or via the act of transcription . We describe here a ribozyme-based approach...
3.
Welte T, Tuck A, Papasaikas P, Carl S, Flemr M, Knuckles P, et al.
Genes Dev
. 2019 Aug;
33(17-18):1221-1235.
PMID: 31371437
TRIM71/LIN-41, a phylogenetically conserved regulator of development, controls stem cell fates. Mammalian TRIM71 exhibits both RNA-binding and protein ubiquitylation activities, but the functional contribution of either activity and relevant primary...
4.
Tuck A, Natarajan K, Rice G, Borawski J, Mohn F, Rankova A, et al.
Life Sci Alliance
. 2018 Nov;
1(4):e201800124.
PMID: 30456373
Eukaryotic genomes produce RNAs lacking protein-coding potential, with enigmatic roles. We integrated three approaches to study large intervening noncoding RNA (lincRNA) gene functions. First, we profiled mouse embryonic stem cells...
5.
Holmes R, Tuck A, Zhu C, Dunn-Davies H, Kudla G, Clauder-Munster S, et al.
PLoS Genet
. 2015 Dec;
11(12):e1005735.
PMID: 26694144
Yeast Npl3 is a highly abundant, nuclear-cytoplasmic shuttling, RNA-binding protein, related to metazoan SR proteins. Reported functions of Npl3 include transcription elongation, splicing and RNA 3' end processing. We used...
6.
Kolodziejczyk A, Kim J, Tsang J, Ilicic T, Henriksson J, Natarajan K, et al.
Cell Stem Cell
. 2015 Oct;
17(4):471-85.
PMID: 26431182
Embryonic stem cell (ESC) culture conditions are important for maintaining long-term self-renewal, and they influence cellular pluripotency state. Here, we report single cell RNA-sequencing of mESCs cultured in three different...
7.
Tuck A, Tollervey D
Mol Cell
. 2012 Feb;
45(4):435-6.
PMID: 22365825
In this issue of Molecular Cell, single-cell analyses by Bumgarner et al. (2012) reveal how two antagonistic long noncoding RNAs at the FLO11 locus define a toggle responsible for morphological...
8.
Tuck A, Tollervey D
Trends Genet
. 2011 Jul;
27(10):422-32.
PMID: 21741109
Eukaryotic genomes accommodate numerous types of information within diverse DNA and RNA sequence elements. At many loci, these elements overlap and the same sequence is read multiple times during the...
9.
Worrall J, Gorna M, Crump N, Phillips L, Tuck A, Price A, et al.
J Mol Biol
. 2008 Aug;
382(4):870-83.
PMID: 18691600
The Escherichia coli RNA degradosome is a multienzyme assembly that functions in transcript turnover and maturation of structured RNA precursors. We have developed a procedure to reconstitute the RNA degradosome...