Alessandra Stangherlin
Overview
Explore the profile of Alessandra Stangherlin including associated specialties, affiliations and a list of published articles.
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31
Citations
947
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Recent Articles
1.
Rodriguez S, Crosby P, Hansen L, Grunewald E, Beale A, Spangler R, et al.
bioRxiv
. 2024 Apr;
PMID: 38617352
Circadian (~24 h) rhythms are a fundamental feature of life, and their disruption increases the risk of infectious diseases, metabolic disorders, and cancer. Circadian rhythms couple to the cell cycle...
2.
Watson J, Seinkmane E, Styles C, Mihut A, Kruger L, McNally K, et al.
Nature
. 2024 Apr;
628(8009):E4.
PMID: 38589575
No abstract available.
3.
Watson J, Seinkmane E, Styles C, Mihut A, Kruger L, McNally K, et al.
Nature
. 2023 Oct;
623(7988):842-852.
PMID: 37853127
Optimum protein function and biochemical activity critically depends on water availability because solvent thermodynamics drive protein folding and macromolecular interactions. Reciprocally, macromolecules restrict the movement of 'structured' water molecules within...
4.
Stangherlin A
Am J Physiol Cell Physiol
. 2023 Jan;
324(3):C632-C643.
PMID: 36689675
Circadian rhythms in physiology and behavior allow organisms to anticipate the daily environmental changes imposed by the rotation of our planet around its axis. Although these rhythms eventually manifest at...
5.
Stangherlin A, Seinkmane E, ONeill J
Curr Opin Syst Biol
. 2021 Dec;
28:None.
PMID: 34950808
Circadian rhythms are ∼24 h cycles of organismal and cellular activity ubiquitous to mammalian physiology. A prevailing paradigm suggests that timing information flows linearly from rhythmic transcription via protein abundance...
6.
Hayter E, Wehrens S, Van Dongen H, Stangherlin A, Gaddameedhi S, Crooks E, et al.
Nat Commun
. 2021 Dec;
12(1):7284.
PMID: 34880252
No abstract available.
7.
Wong D, Seinkmane E, Zeng A, Stangherlin A, Rzechorzek N, Beale A, et al.
EMBO J
. 2021 Nov;
41(1):e108883.
PMID: 34842284
The daily organisation of most mammalian cellular functions is attributed to circadian regulation of clock-controlled protein expression, driven by daily cycles of CRYPTOCHROME-dependent transcriptional feedback repression. To test this, we...
8.
Stangherlin A, Watson J, Wong D, Barbiero S, Zeng A, Seinkmane E, et al.
Nat Commun
. 2021 Nov;
12(1):6988.
PMID: 34819501
No abstract available.
9.
Stangherlin A, Watson J, Wong D, Barbiero S, Zeng A, Seinkmane E, et al.
Nat Commun
. 2021 Oct;
12(1):6035.
PMID: 34654800
Between 6-20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the...
10.
Kay H, Grunewald E, Feord H, Gil S, Peak-Chew S, Stangherlin A, et al.
Commun Biol
. 2021 Oct;
4(1):1147.
PMID: 34593975
The cellular landscape changes dramatically over the course of a 24 h day. The proteome responds directly to daily environmental cycles and is additionally regulated by the circadian clock. To...