Emmanuel Derivery
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Explore the profile of Emmanuel Derivery including associated specialties, affiliations and a list of published articles.
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51
Citations
1832
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Recent Articles
1.
Planelles-Herrero V, Genova M, Kruger L, Bittleston A, McNally K, Morgan T, et al.
EMBO J
. 2025 Jan;
44(5):1322-1353.
PMID: 39815006
Elongator is a tRNA-modifying complex that regulates protein translation. Recently, a moonlighting function of Elongator has been identified in regulating the polarization of the microtubule cytoskeleton during asymmetric cell division....
2.
Kruger L, Watson J, Derivery E
Methods Mol Biol
. 2024 Dec;
2872:247-255.
PMID: 39616581
During asymmetric cell division, cortical polarity cues drive the polarization of the microtubule cytoskeleton to ensure the generation of two daughter cells with different fates. While this a critical process...
3.
Shen H, Lynch E, Watson J, Wu K, Bai H, Sheffler W, et al.
bioRxiv
. 2024 Sep;
PMID: 39345553
The design of inducibly assembling protein nanomaterials is an outstanding challenge. Here, we describe the computational design of a protein filament formed from a monomeric subunit which binds a peptide...
4.
Wu K, Jiang H, Hicks D, Liu C, Muratspahic E, Ramelot T, et al.
bioRxiv
. 2024 Jul;
PMID: 39071356
Intrinsically disordered proteins and peptides play key roles in biology, but the lack of defined structures and the high variability in sequence and conformational preferences has made targeting such systems...
5.
Salvador-Garcia D, Jin L, Hensley A, Golcuk M, Gallaud E, Chaaban S, et al.
J Cell Biol
. 2024 Jul;
223(10).
PMID: 38949648
The diverse roles of the dynein motor in shaping microtubule networks and cargo transport complicate in vivo analysis of its functions significantly. To address this issue, we have generated a...
6.
Watson J, Seinkmane E, Styles C, Mihut A, Kruger L, McNally K, et al.
Nature
. 2024 Apr;
628(8009):E4.
PMID: 38589575
No abstract available.
7.
Shen H, Lynch E, Akkineni S, Watson J, Decarreau J, Bethel N, et al.
Nat Nanotechnol
. 2024 Apr;
19(7):1016-1021.
PMID: 38570702
Biological evolution has led to precise and dynamic nanostructures that reconfigure in response to pH and other environmental conditions. However, designing micrometre-scale protein nanostructures that are environmentally responsive remains a...
8.
Madan V, Albacete-Albacete L, Jin L, Scaturro P, Watson J, Muschalik N, et al.
EMBO J
. 2023 Oct;
42(23):e114473.
PMID: 37872872
The microtubule motor dynein mediates polarised trafficking of a wide variety of organelles, vesicles and macromolecules. These functions are dependent on the dynactin complex, which helps recruit cargoes to dynein's...
9.
Canon L, Kikuti C, Planelles-Herrero V, Lin T, Mayeux F, Sirkia H, et al.
Nat Commun
. 2023 Oct;
14(1):6732.
PMID: 37872146
Myosin VI (Myo6) is the only minus-end directed nanomotor on actin, allowing it to uniquely contribute to numerous cellular functions. As for other nanomotors, the proper functioning of Myo6 relies...
10.
Watson J, Seinkmane E, Styles C, Mihut A, Kruger L, McNally K, et al.
Nature
. 2023 Oct;
623(7988):842-852.
PMID: 37853127
Optimum protein function and biochemical activity critically depends on water availability because solvent thermodynamics drive protein folding and macromolecular interactions. Reciprocally, macromolecules restrict the movement of 'structured' water molecules within...