Andrew D Beale
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Explore the profile of Andrew D Beale including associated specialties, affiliations and a list of published articles.
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Citations
311
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Recent Articles
1.
Munns J, Beale A, Michaelides I, Peak-Chew S, Mihut A, Major-Styles C, et al.
Philos Trans R Soc Lond B Biol Sci
. 2025 Jan;
380(1918):20230342.
PMID: 39842482
The mammalian cryptochrome proteins (CRY1 and CRY2) are transcriptional repressors most notable for their role in circadian transcriptional feedback. Not all circadian rhythms depend on CRY proteins, however, and the...
2.
de Andrade T, Beale A
PNAS Nexus
. 2024 Aug;
3(8):pgae318.
PMID: 39192844
While the formalization of chronobiology as a scientific discipline occurred in the mid-20th century, the exploration of rhythmic phenomena has a longer history, notably exemplified by De Mairan's observations of...
3.
Seinkmane E, Edmondson A, Peak-Chew S, Zeng A, Rzechorzek N, James N, et al.
EMBO J
. 2024 May;
43(13):2813-2833.
PMID: 38778155
Although costly to maintain, protein homeostasis is indispensable for normal cellular function and long-term health. In mammalian cells and tissues, daily variation in global protein synthesis has been observed, but...
4.
Rodriguez S, Crosby P, Hansen L, Grunewald E, Beale A, Spangler R, et al.
bioRxiv
. 2024 Apr;
PMID: 38617352
Circadian (~24 h) rhythms are a fundamental feature of life, and their disruption increases the risk of infectious diseases, metabolic disorders, and cancer. Circadian rhythms couple to the cell cycle...
5.
Watson J, Seinkmane E, Styles C, Mihut A, Kruger L, McNally K, et al.
Nature
. 2024 Apr;
628(8009):E4.
PMID: 38589575
No abstract available.
6.
Watson J, Seinkmane E, Styles C, Mihut A, Kruger L, McNally K, et al.
Nature
. 2023 Oct;
623(7988):842-852.
PMID: 37853127
Optimum protein function and biochemical activity critically depends on water availability because solvent thermodynamics drive protein folding and macromolecular interactions. Reciprocally, macromolecules restrict the movement of 'structured' water molecules within...
7.
Beale A, Hayter E, Crosby P, Valekunja U, Edgar R, Chesham J, et al.
EMBO J
. 2023 Aug;
42(19):e114164.
PMID: 37554073
Cellular circadian rhythms confer temporal organisation upon physiology that is fundamental to human health. Rhythms are present in red blood cells (RBCs), the most abundant cell type in the body,...
8.
Labeed F, Beale A, Schneider P, Kitcatt S, Kruchek E, Reece S
Front Bioeng Biotechnol
. 2022 Nov;
10:994487.
PMID: 36440448
Circadian rhythms are biological adaptations to the day-night cycle, whereby cells adapt to changes in the external environment or internal physiology according to the time of day. Whilst many cellular...
9.
Beale A, Labeed F, Kitcatt S, ONeill J
Methods Mol Biol
. 2022 May;
2482:255-264.
PMID: 35610432
Dielectrophoresis (DEP) enables the measurement of population-level electrophysiology in many cell types by examining their interaction with an externally applied electric field. Here we describe the application of DEP to...
10.
ONeill J, Hoyle N, Robertson J, Edgar R, Beale A, Peak-Chew S, et al.
Nat Commun
. 2021 Dec;
12(1):7269.
PMID: 34880246
No abstract available.