Alessandra Silvani
Overview
Explore the profile of Alessandra Silvani including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
61
Citations
320
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Citarella A, Fiori A, Silvani A, Passarella D, Fasano V
ChemSusChem
. 2025 Jan;
:e202402538.
PMID: 39831740
The first successful synthesis of 1,2,3-triazoles using Cyrene as a biodegradable and non-toxic solvent in click chemistry has been developed. In contrast to previous methods, this sustainable approach allows product...
2.
Citarella A, Petrella S, Moi D, Dimasi A, Braga T, Ruberto L, et al.
Bioorg Med Chem
. 2024 Nov;
115:117987.
PMID: 39509759
Cathepsins, key members of the papain-like family of cysteine proteases, are crucial for proteolysis processes within human cells, including osteolysis, immunomodulation and apoptosis. Recent research has highlighted the significant role...
3.
Citarella A, Cavinato M, Rosini E, Shehi H, Ballabio F, Camilloni C, et al.
ACS Med Chem Lett
. 2024 Sep;
15(9):1474-1481.
PMID: 39291031
A library of novel nicotinic acid derivatives, focusing on the modification of position 6 of the pyridine ring with (thio)ether functionalities, was mostly produced through an innovative green synthetic approach...
4.
Fassi E, Citarella A, Albani M, Milano E, Legnani L, Lammi C, et al.
Expert Opin Ther Pat
. 2024 Apr;
34(4):245-261.
PMID: 38588538
Introduction: Proprotein convertase subtilisin/kexin 9 (PCSK9) plays a crucial role in breaking down the hepatic low-density lipoprotein receptor (LDLR), thereby influencing the levels of circulating low-density lipoprotein cholesterol (LDL-C). Consequently,...
5.
Manenti M, Villa T, Macetti G, Silvani A
Org Biomol Chem
. 2024 Feb;
22(10):2124-2136.
PMID: 38376537
A one-pot protocol, consisting of a Pd-catalysed carboamination reaction, followed by -deprotection and oxidative denitrogenation, has been developed for the synthesis of diversely substituted spirocyclopropyloxindoles, in yields up to 73%...
6.
Lammi C, Fassi E, Manenti M, Brambilla M, Conti M, Li J, et al.
J Med Chem
. 2023 Jun;
66(12):7943-7958.
PMID: 37261954
Proprotein convertase subtilisin/kexin 9 (PCSK9) is responsible for the degradation of the hepatic low-density lipoprotein receptor (LDLR), which regulates circulating cholesterol levels. Consequently, the PCSK9 inhibition is a valuable therapeutic...
7.
Citarella A, Moi D, Pedrini M, Perez-Pena H, Pieraccini S, Dimasi A, et al.
Org Biomol Chem
. 2023 Apr;
21(18):3811-3824.
PMID: 37078164
COVID-19 now ranks among the most devastating global pandemics in history. The causative virus, SARS-CoV-2, is a new human coronavirus (hCoV) that spreads among humans and animals. Great efforts have...
8.
Fassi E, Manenti M, Citarella A, Cas M, Casati S, Micale N, et al.
Molecules
. 2023 Mar;
28(5).
PMID: 36903597
The COVID-19 pandemic has given a strong impetus to the search for antivirals active on SARS-associated coronaviruses. Over these years, numerous vaccines have been developed and many of these are...
9.
Citarella A, Moi D, Pedrini M, Perez-Pena H, Pieraccini S, Stagno C, et al.
Molecules
. 2023 Jan;
28(2).
PMID: 36677572
SARS-CoV-2 M is a chymotrypsin-like cysteine protease playing a relevant role during the replication and infectivity of SARS-CoV-2, the coronavirus responsible for COVID-19. The binding site of M is characterized...
10.
Manenti M, Gusmini S, Lo Presti L, Molteni G, Silvani A
Mol Divers
. 2022 Oct;
27(5):2161-2168.
PMID: 36258147
Various boron-containing isocyanides have been efficiently synthesized from the corresponding enantiopure β-substituted β-amino boronic acid pinacol esters, without need for protecting group interconversion, through a two-step, purification-free procedure. They were...