Alena Salasova
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Explore the profile of Alena Salasova including associated specialties, affiliations and a list of published articles.
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10
Citations
168
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Recent Articles
1.
Emerging potential of progranulin-dependent SorCS2 signaling in healthy and diseased nervous systems
Salasova A, Nykjaer A
Neural Regen Res
. 2024 Nov;
20(9):2591-2593.
PMID: 39503427
No abstract available.
2.
Ho K, Trapp M, Guida C, Ivanova E, De Jaime-Soguero A, Jabali A, et al.
Neuro Oncol
. 2024 Aug;
27(1):106-122.
PMID: 39215664
Background: The choroid plexus (ChP) is the secretory epithelial structure located in the brain ventricles. Choroid plexus tumors (CPTs) are rare neoplasms predominantly occurring in young patients with intensified malignancy...
3.
Thomasen P, Salasova A, Kjaer-Sorensen K, Woloszczukova L, Lavicky J, Login H, et al.
Cell Rep
. 2023 Oct;
42(11):113333.
PMID: 37897724
Motor neuron (MN) development and nerve regeneration requires orchestrated action of a vast number of molecules. Here, we identify SorCS2 as a progranulin (PGRN) receptor that is required for MN...
4.
Salasova A, Monti G, Andersen O, Nykjaer A
Mol Neurodegener
. 2022 Nov;
17(1):74.
PMID: 36397124
The family of VPS10p-Domain (D) receptors comprises five members named SorLA, Sortilin, SorCS1, SorCS2 and SorCS3. While their physiological roles remain incompletely resolved, they have been recognized for their signaling...
5.
Kaiser K, Gyllborg D, Prochazka J, Salasova A, Kompanikova P, Molina F, et al.
Nat Commun
. 2019 Apr;
10(1):1498.
PMID: 30940800
WNTs are lipid-modified proteins that control multiple functions in development and disease via short- and long-range signaling. However, it is unclear how these hydrophobic molecules spread over long distances in...
6.
Bostrom J, Sramkova Z, Salasova A, Johard H, Mahdessian D, Fedr R, et al.
PLoS One
. 2017 Dec;
12(12):e0188772.
PMID: 29228002
The cell cycle coordinates core functions such as replication and cell division. However, cell-cycle-regulated transcription in the control of non-core functions, such as cell identity maintenance through specific transcription factors...
7.
Salasova A, Yokota C, Potesil D, Zdrahal Z, Bryja V, Arenas E
Mol Neurodegener
. 2017 Jul;
12(1):54.
PMID: 28697798
Background: Autosomal-dominant mutations in the Park8 gene encoding Leucine-rich repeat kinase 2 (LRRK2) have been identified to cause up to 40% of the genetic forms of Parkinson's disease. However, the...
8.
Cervenka I, Valnohova J, Bernatik O, Harnos J, Radsetoulal M, Sedova K, et al.
Proc Natl Acad Sci U S A
. 2016 Aug;
113(33):9304-9.
PMID: 27486244
Dishevelled (DVL) is a key scaffolding protein and a branching point in Wnt signaling pathways. Here, we present conclusive evidence that DVL regulates the centrosomal cycle. We demonstrate that DVL...
9.
Mansson-Broberg A, Rodin S, Bulatovic I, Ibarra C, Lofling M, Genead R, et al.
Stem Cell Reports
. 2016 Apr;
6(4):607-617.
PMID: 27052314
The intrinsic regenerative capacity of human fetal cardiac mesenchymal stromal cells (MSCs) has not been fully characterized. Here we demonstrate that we can expand cells with characteristics of cardiovascular progenitor...
10.
Krejci P, Salazar L, Kashiwada T, Chlebova K, Salasova A, Thompson L, et al.
PLoS One
. 2008 Dec;
3(12):e3961.
PMID: 19088846
Activating mutations in FGFR3 tyrosine kinase cause several forms of human skeletal dysplasia. Although the mechanisms of FGFR3 action in cartilage are not completely understood, it is believed that the...