Andrzej W Lipkowski
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Explore the profile of Andrzej W Lipkowski including associated specialties, affiliations and a list of published articles.
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77
Citations
518
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Recent Articles
1.
Sowinska M, Morawiak M, Bochynska-Czyz M, Lipkowski A, Zieminska E, Zablocka B, et al.
Biomolecules
. 2019 Mar;
9(3).
PMID: 30841638
Exposure to ozone level and ultraviolet (UV) radiation is one of the major concerns in the context of public health. Numerous studies confirmed that abundant free radicals initiate undesired processes,...
2.
Sowinska M, Laskowska A, Guspiel A, Solecka J, Bochynska-Czyz M, Lipkowski A, et al.
Bioconjug Chem
. 2018 Sep;
29(11):3571-3585.
PMID: 30235928
Evolution-derived natural compounds have been inspirational for design of numerous pharmaceuticals, e.g., penicillins and tetracyclines. Herein, we present a bioinspired strategy to design peptide dendrimers for the effective therapy of...
3.
Dyniewicz J, Lipinski P, Kosson P, Lesniak A, Bochynska-Czyz M, Muchowska A, et al.
ACS Med Chem Lett
. 2017 Jan;
8(1):73-77.
PMID: 28105278
The area of multitarget compounds, joining two pharmacophores within one molecule, is a vivid field of research in medicinal chemistry. Not only pharmacophoric elements are essential for the design and...
4.
Kaczynska K, Wojciechowski P, Jampolska M, Lipkowski A, Kleczkowska P
Eur J Pharmacol
. 2017 Jan;
797:20-25.
PMID: 28089918
Aim: Chimeric compound - PK20 despite its therapeutic activity on nociceptive and inflammatory processes may affect respiration and blood pressure. Our objective was to evaluate influence of the hybrid composed...
5.
Konop M, Sulejczak D, Czuwara J, Kosson P, Misicka A, Lipkowski A, et al.
Wound Repair Regen
. 2016 Dec;
25(1):62-74.
PMID: 27997709
Keratin is an interesting protein needed for wound healing and tissue recovery. We have recently proposed a new, simple and inexpensive method to obtain fur and hair keratin-derived biomaterials suitable...
6.
Kaczynska K, Kogut E, Zajac D, Jampolska M, Andrzejewski K, Sulejczak D, et al.
Eur J Pharm Sci
. 2016 Aug;
93:84-9.
PMID: 27509866
The objective of the study was to investigate the possibility of modulation of skin inflammation by topical treatment with a novel compound: an opioid-neurotensin hybrid peptide PK20 encompassing endomorphin-2 analog...
7.
Badzynska B, Lipkowski A, Olszynski K, Sadowski J
Can J Physiol Pharmacol
. 2016 Aug;
94(11):1159-1169.
PMID: 27494747
Opioids interact with sympathetic and renin-angiotensin systems in control of mean arterial pressure (MAP). Our earlier finding that biphalin, a synthetic enkephalin analogue, decreased MAP in anaesthetized spontaneously hypertensive rats...
8.
Kleczkowska P, Hermans E, Kosson P, Kowalczyk A, Lesniak A, Pawlik K, et al.
Brain Res
. 2016 Jul;
1648(Pt A):172-180.
PMID: 27473894
Hybrid compounds are suggested to be a more effective remedy for treatment of various diseases than combination therapy, since the attenuation or total disappearance of side effects, typically induced by...
9.
Kowalczyk A, Kleczkowska P, Rekawek M, Kulik K, Lesniak A, Erdei A, et al.
Eur J Pharm Sci
. 2016 Jul;
93:11-20.
PMID: 27423260
The design of novel drugs for pain relief with improved analgesic properties and diminished side effect induction profile still remains a challenging pursuit. Tolerance is one of the most burdensome...
10.
Lesniak A, Bochynska-Czyz M, Sacharczuk M, Benhye S, Misicka A, Bujalska-Zadrozny M, et al.
Eur J Pharm Sci
. 2016 Apr;
89:39-49.
PMID: 27094782
The search for new drugs for cancer pain management has been a long-standing goal in basic and clinical research. Classical opioid drugs exert their primary antinociceptive effect upon activating opioid...