Alejandro Torres-Hernandez
Overview
Explore the profile of Alejandro Torres-Hernandez including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
26
Citations
2021
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Torres-Hernandez A, Wang W, Nikiforov Y, Tejada K, Torres L, Kalabin A, et al.
Oncogene
. 2019 Feb;
38(23):4512-4526.
PMID: 30742098
Liver fibrosis and fibrosis-associated hepatocarcinogenesis are driven by chronic inflammation and are leading causes of morbidity and death worldwide. SYK signaling regulates critical processes in innate and adaptive immunity, as...
12.
Grunhut J, Wang W, Aykut B, Gakhal I, Torres-Hernandez A, Miller G
Eur Med J Hepatol
. 2018 Jun;
6(1):100-109.
PMID: 29930864
Nonalcoholic steatohepatitis (NASH) is a subtype of nonalcoholic fatty liver disease that is characterised by steatosis, chronic inflammation, and hepatocellular injury with or without fibrosis. The role and activation of...
13.
Pushalkar S, Hundeyin M, Daley D, Zambirinis C, Kurz E, Mishra A, et al.
Cancer Discov
. 2018 Mar;
8(4):403-416.
PMID: 29567829
We found that the cancerous pancreas harbors a markedly more abundant microbiome compared with normal pancreas in both mice and humans, and select bacteria are differentially increased in the tumorous...
14.
Daley D, Mani V, Mohan N, Akkad N, Pandian G, Savadkar S, et al.
J Exp Med
. 2017 Apr;
214(6):1711-1724.
PMID: 28442553
The tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDA) is characterized by immune tolerance, which enables disease to progress unabated by adaptive immunity. However, the drivers of this tolerogenic program...
15.
Daley D, Mani V, Mohan N, Akkad N, Ochi A, Heindel D, et al.
Nat Med
. 2017 Apr;
23(5):556-567.
PMID: 28394331
The progression of pancreatic oncogenesis requires immune-suppressive inflammation in cooperation with oncogenic mutations. However, the drivers of intratumoral immune tolerance are uncertain. Dectin 1 is an innate immune receptor crucial...
16.
Torres-Hernandez A, Miller G
Gastroenterology
. 2016 Oct;
151(5):807-808.
PMID: 27702557
No abstract available.
17.
Daley D, Zambirinis C, Seifert L, Akkad N, Mohan N, Werba G, et al.
Cell
. 2016 Aug;
166(6):1485-1499.e15.
PMID: 27569912
Inflammation is paramount in pancreatic oncogenesis. We identified a uniquely activated γδT cell population, which constituted ∼40% of tumor-infiltrating T cells in human pancreatic ductal adenocarcinoma (PDA). Recruitment and activation...
18.
Greco S, Torres-Hernandez A, Kalabin A, Whiteman C, Rokosh R, Ravirala S, et al.
J Immunol
. 2016 Aug;
197(7):2816-27.
PMID: 27559045
Con A hepatitis is regarded as a T cell-mediated model of acute liver injury. Mincle is a C-type lectin receptor that is critical in the immune response to mycobacteria and...
19.
Seifert L, Werba G, Tiwari S, Ly N, Alothman S, Alqunaibit D, et al.
Nature
. 2016 Apr;
532(7598):245-9.
PMID: 27049944
Neoplastic pancreatic epithelial cells are believed to die through caspase 8-dependent apoptotic cell death, and chemotherapy is thought to promote tumour apoptosis. Conversely, cancer cells often disrupt apoptosis to survive....
20.
Radiation Therapy Induces Macrophages to Suppress T-Cell Responses Against Pancreatic Tumors in Mice
Seifert L, Werba G, Tiwari S, Ly N, Nguy S, Alothman S, et al.
Gastroenterology
. 2016 Mar;
150(7):1659-1672.e5.
PMID: 26946344
Background & Aims: The role of radiation therapy in the treatment of patients with pancreatic ductal adenocarcinoma (PDA) is controversial. Randomized controlled trials investigating the efficacy of radiation therapy in...