Alberto R Kornblihtt
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Explore the profile of Alberto R Kornblihtt including associated specialties, affiliations and a list of published articles.
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91
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5309
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Recent Articles
1.
Kubaczka M, Godoy Herz M, Chen W, Zheng D, Petrillo E, Tian B, et al.
Proc Natl Acad Sci U S A
. 2024 Aug;
121(34):e2405632121.
PMID: 39150783
Transcription of eukaryotic protein-coding genes generates immature mRNAs that are subjected to a series of processing events, including capping, splicing, cleavage, and polyadenylation (CPA), and chemical modifications of bases. Alternative...
2.
Manavella P, Godoy Herz M, Kornblihtt A, Sorenson R, Sieburth L, Nakaminami K, et al.
Plant Cell
. 2022 Dec;
35(6):1626-1653.
PMID: 36477566
The study of RNAs has become one of the most influential research fields in contemporary biology and biomedicine. In the last few years, new sequencing technologies have produced an explosion...
3.
Marasco L, Kornblihtt A
Nat Rev Mol Cell Biol
. 2022 Oct;
24(4):242-254.
PMID: 36229538
Alternative splicing is a substantial contributor to the high complexity of transcriptomes of multicellular eukaryotes. In this Review, we discuss the accumulated evidence that most of this complexity is reflected...
4.
Marasco L, Dujardin G, Sousa-Luis R, Liu Y, Stigliano J, Nomakuchi T, et al.
Cell
. 2022 Jun;
185(12):2057-2070.e15.
PMID: 35688133
Spinal muscular atrophy (SMA) is a motor-neuron disease caused by mutations of the SMN1 gene. The human paralog SMN2, whose exon 7 (E7) is predominantly skipped, cannot compensate for the...
5.
Nazer E, Kornblihtt A
Proc Natl Acad Sci U S A
. 2021 Dec;
118(52).
PMID: 34949645
No abstract available.
6.
Nazer E, Gomez Acuna L, Kornblihtt A
Mol Cell
. 2021 Dec;
82(3):503-513.
PMID: 34856122
Argonaute proteins have been traditionally characterized as a highly evolutionary conserved family engaged in post-transcriptional gene silencing pathways. The Argonaute family is mainly grouped into the AGO and PIWI clades....
7.
Wightman F, Godoy Herz M, Munoz J, Stigliano J, Bragado L, Nieto Moreno N, et al.
RNA Biol
. 2021 May;
18(12):2218-2225.
PMID: 33966602
Early detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been proven crucial during the efforts to mitigate the effects of the COVID-19 pandemic. Several diagnostic methods have...
8.
Giono L, Kornblihtt A
Biochem J
. 2020 Aug;
477(16):3091-3104.
PMID: 32857854
Gene expression is an intricately regulated process that is at the basis of cell differentiation, the maintenance of cell identity and the cellular responses to environmental changes. Alternative splicing, the...
9.
Gomez Acuna L, Nazer E, Rodriguez-Segui S, Pozzi B, Buggiano V, Marasco L, et al.
J Cell Biol
. 2020 Jul;
219(9).
PMID: 32673398
In mammals, argonaute (AGO) proteins have been characterized for their roles in small RNA-mediated posttranscriptional and also in transcriptional gene silencing. Here, we report a different role for AGO1 in...
10.
Wilson C, Giono L, Rozes-Salvador V, Fiszbein A, Kornblihtt A, Caceres A
Cell Rep
. 2020 May;
31(6):107639.
PMID: 32402271
The generation of axonal and dendritic domains is critical for brain circuitry assembly and physiology. Negative players, such as the RhoA-Rho coiled-coil-associated protein kinase (ROCK) signaling pathway, restrain axon development...