Anabella Srebrow
Overview
Explore the profile of Anabella Srebrow including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
1016
Followers
0
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Recent Articles
1.
Bragado L, Magalnik M, Mammi P, Romero A, Gaioli N, Pozzi B, et al.
Nucleic Acids Res
. 2022 Dec;
50(21):12444-12461.
PMID: 36454007
RNA polymerase II (RNAPII) transcribes small nuclear RNA (snRNA) genes in close proximity to Cajal bodies, subnuclear compartments that depend on the SUMO isopeptidase USPL1 for their assembly. We show...
2.
Wightman F, Godoy Herz M, Munoz J, Stigliano J, Bragado L, Nieto Moreno N, et al.
RNA Biol
. 2021 May;
18(12):2218-2225.
PMID: 33966602
Early detection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been proven crucial during the efforts to mitigate the effects of the COVID-19 pandemic. Several diagnostic methods have...
3.
Pozzi B, Bragado L, Mammi P, Torti M, Gaioli N, Gebhard L, et al.
Nucleic Acids Res
. 2020 May;
48(12):6824-6838.
PMID: 32432721
RNA-seq experiments previously performed by our laboratories showed enrichment in intronic sequences and alterations in alternative splicing in dengue-infected human cells. The transcript of the SAT1 gene, of well-known antiviral...
4.
Tocci J, Felcher C, Sola M, Goddio M, Zimberlin M, Rubinstein N, et al.
Cancer Res
. 2018 May;
78(16):4497-4511.
PMID: 29748375
R-spondin3 (RSPO3) is a member of a family of secreted proteins that enhance Wnt signaling pathways in diverse processes, including cancer. However, the role of RSPO3 in mammary gland and...
5.
Pozzi B, Mammi P, Bragado L, Giono L, Srebrow A
RNA Biol
. 2018 May;
15(6):689-695.
PMID: 29741121
Spliceosomal proteins have been revealed as SUMO conjugation targets. Moreover, we have reported that many of these are in a SUMO-conjugated form when bound to a pre-mRNA substrate during a...
6.
Pozzi B, Bragado L, Will C, Mammi P, Risso G, Urlaub H, et al.
Nucleic Acids Res
. 2017 Apr;
45(11):6729-6745.
PMID: 28379520
Pre-mRNA splicing is catalyzed by the spliceosome, a multi-megadalton ribonucleoprotein machine. Previous work from our laboratory revealed the splicing factor SRSF1 as a regulator of the SUMO pathway, leading us...
7.
De Maio F, Risso G, Iglesias N, Shah P, Pozzi B, Gebhard L, et al.
PLoS Pathog
. 2016 Aug;
12(8):e1005841.
PMID: 27575636
Dengue virus NS5 protein plays multiple functions in the cytoplasm of infected cells, enabling viral RNA replication and counteracting host antiviral responses. Here, we demonstrate a novel function of NS5...
8.
Bertolin A, Katz M, Yano M, Pozzi B, Acevedo J, Blanco-Obregon D, et al.
Nucleic Acids Res
. 2016 May;
44(16):7555-67.
PMID: 27141964
Adaptation to hypoxia depends on a conserved α/β heterodimeric transcription factor called Hypoxia Inducible Factor (HIF), whose α-subunit is regulated by oxygen through different concurrent mechanisms. In this study, we...
9.
Fiszbein A, Giono L, Quaglino A, Berardino B, Sigaut L, von Bilderling C, et al.
Cell Rep
. 2016 Mar;
14(12):2797-808.
PMID: 26997278
Chromatin modifications are critical for the establishment and maintenance of differentiation programs. G9a, the enzyme responsible for histone H3 lysine 9 dimethylation in mammalian euchromatin, exists as two isoforms with...
10.
Risso G, Blaustein M, Pozzi B, Mammi P, Srebrow A
Biochem J
. 2015 May;
468(2):203-14.
PMID: 25997832
Akt/PKB, a serine/threonine kinase member of the AGC family of proteins, is involved in the regulation of a plethora of cellular processes triggered by a wide diversity of extracellular signals...